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72 Cards in this Set

  • Front
  • Back

Fungi

most common plant pathogens

Human mycoses

caused by fungal pathogens and opportunistic pathogens

Thermal Dimorphism

When fungal spores from the environment gainentrance to a warm-blooded animal, they germinate into yeasts and remain inthis phase in the host




Yeastcells leaving the animal host return to the environment and revert to thesporulating hyphal state

Mycology

Study of Fungi

Yeasts

Unicellular


Budding yeasts

Dimorphism

yeast-like at 37C


mold-like at 25C

True pathogen

Systemic - deep within body


Subcutaneous - beneath skin


cutaneous - hair, skin, and nails


Opportunistic


Weakened host

Histoplasma


Blastomyces

eastern coast of US

Ringworm

contagous


scalp, body, feet, or nails


Transmitted skin-to-skin, indirect contact

Dermatophytes

ringworm and tinea

Trichophyton

Fungal cause #1


Itchy, red, raised, scaly patches – may blister, ooze


Scalp of beard: bald patches


Nails: discolored, thick, crumble

Tinea capitis

ringworm of scalp

tinea barbae

ringworm of beard

tinea corporis

ringworm of body

Epidermophyton

"jock itch"

Sporotrichosis

subcutaneous infection


gardeners and farmers

Blastomycoses

subcutaneous


attacks weak

Blastomyces Dermatitis

North American Blastomyces


inhaled


cutaneous, bone, and nervous system complications

Coccidoides Infection

San Joaquin Valley Fever


Digging ins oil produces aerosol of arthrospores


Lung infection

Histoplasma

Ohio Valley Fever


soil containing bird dropping is whipped up by the wind

Cryptococcus

deadly if bad T cells


depends on host's immunity

Cryptococcus neoforms

yeast with capsule


inhabits soil around pigeon roots



Candida Albicans

normal flora


70% of nosocomial fungal infections


Trush


Vaginitis


Cutaneous candidiasis

Candida

Pain, redness, white coating/discharge


Causes:


antibiotics - kill normal flora


pregnancy & oral contraceptives


diabetes, steroids


T cell deficiency

Aspergillosis

Acute pulmonary infection

Pneumocystis

Pneumocystis jiroveci


leading cause of illness and death in impaired immune system patients

Amanita

death cap mushroom



Claviceps

hallucinations


LSD precursor

Archaezoa

the ancient ones


no mitochondria


multiple flagella move them

Euglena

complex cell flagellates

Giardia

Active in gut


Inactive cyst survive for monthsin environment

Trichomonas vaginalis

STD


no symptoms

Hemo Flagellates

blood borne

Trypanosoma


Leishmania


Trypanosoma

sleeping sickness spread by tse tse fly

Trypanosoma cruzi

chaga's disease


heart muscle and large intestine harbor masses of amastigotes


chronic inflammation


eye swells at bite wound

Leshmania

first: skin reactions


visceral: fever, weight loss, swelling of liver & spleen, anemia

Entamoeba hystolitica

transmitted by fecal contamination


infection = GI stress or blockage


asymptomatic in 90% patients

Naegleria fowleri


Acanthameba

causes amoebic infections of the brain

Ciliates

move by cilia


Complex cells


Balantidium coli = only human parasite

Free living ciliate

conjugation, cilia, nucleus

Balantidium coli

GI distress


infects large intestine


severe colitis with ulcerations like amoebic disentery

Sporozoans/Apicocomplans

ALL parasites, non moving, complex life cycles


Have apical complex

Plasmodium

Malaria


spread by female Anopheles fly

Sporozoites

infective cells

Gametocytes

sex cells of parasite

Trophozoite

feeding forms

Zygote

fertilized egg

Toxoplasma

lives naturally in cats that harbor oocysts in the GI tract


acquired by ingesting raw meat or contaminated substances by cat feces

Clycospora

emerging protozoan disease


flu like + watery diarrhea


fecal oral, contaminated veggies


deadly in HIV patients

Cryptosporidium

new recognized intestinal pathogen

Babesia

tick-transmitted


causes malaria-like symptoms and hemolytic anemia

Helminths

parasitic worms

Platyhelminthes

flatworms

Trematodes

Flukes

Cestodes

tapeworms

Nematodes

roundworms

Reproduction: Helminth Parasites

sexes may separate hermaphroditic


Adult and mating occur in definitive primary host


Larval = intermediate host


transport host experiences no parasitic development

Nematodes/roundworms

eggs can be infective to intestine

Ascaris

Intestinal roundworms


in areas of poor sanitation



Ascarias lumbricoides

severe inflammatory reactions mark the migratory route


allergic reactions

Whipworms

mild intestinal parasite Trichuris


Diagnosis: examining stool and finding eggs

Pinworms Enterobius

most common roundworm parasite in US


temperate areas even with good sanitation

Hookworms

curved ends and hooked mouths


Necator


burrow into the skin of bare feet

Trichinella spiralis and Trichinellosis

Life cycle entirely within mammalian host

Onchocerciasis

River Blindness


Transmitted by the bite of small black flies that breed in streams and rivers


Major cause of preventable blindness

Elephantiasis

Filarial roundwoorms


thickening of the skin and tissues, legs, and genitals


Obstruction of lymphatic vessels


Nematodes = lymphatic filariasis


Transmitted by mosquito

Schistosoma

Flatworm


Blood Fluke


second most important infection


contracted swimming, fishing


blind ending digestive system - no anus

Blood Fluke Life Cycle

Adult worm enter blood vessels


Eggs through urine or feces to fresh water


Snail = intermediate host


Larva infects - penetrates skin

Cestode Infestations

Tapeworm


Each proglottid is an independent unit adapted to absorbing food and making and releasing eggs


Taenia saginata


Taenia solium

Tapeworm Life Cycle

Humans can be primary or intermediate host


Larva encyst in our organs

Human primary host

weight loss


vitamin deficiency


rarely, intestinal blockage

Tapeworms

Head or scolex: where worms attach to gut plus neck


Segmented body: contains male and female gonads


Rows of teeth to grab on with


Absorbs nutrients