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21 Cards in this Set
- Front
- Back
____ is a compound on which enzyme "works"
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substrate
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____ is the specific portion of the enzyme where substrate binds
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active site
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____ is the process that makes an inactive nezyme active.
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activation
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____ is any process that makes an enzyme less active or inactive
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inhibition
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Both the lock-and-key model and the induced-fit model emphasize the shape of the ______.
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active site
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The ____ of the active site is the most important.
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chemistry
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5 amino acids that participate in active sites
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His > Cys > Asp > Arg > Glu
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____ is a substance that binds to the active site of an enzyme thus preventing binding of substrate
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competitve inhibitor
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____ is any substnce that binds to a portion of the enzyme other than the active site and thus inhibits the activity of the enzyme.
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noncompetitive inhibitor
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The induced-fit model comparing active site to a glove and substrate to a hand explains _____
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competitive inhibition
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_____ is the binding of a regulator to a site other than the active site changing the shape of the the active site.
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Allosteric effect
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______ is an enzyme-regulation process where the product of a series of enzyme-catalyzed reactions inhibits an earlier reaction in a sequence.
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feedback control
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High concentration of ____ can be used to regulate feedback.
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substrate
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Nerve gas, cyanide, and arsenic are ex. of ____ inhibitors.
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irreversible
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Nerve gas contains lots of ___ groups.
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phosphate
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2 things nerve gas affects
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trysin and chymotrypsin
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What irreversible inhibitor binds to metals?
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cyanide
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_____ is an irreversible inhibitor that substitutes for phosphate.
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arsenic
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3 changes that occur to enzyme modification from inactive to active
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1) hydrolysis of N-terminal end of 6 AA chain
2) changes 3-D structure 3) exposes active site |
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_____ is an enzyme in the inactive form.
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zymogen
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____ is a reversible enzyme that occurs in multiple forms; each catalyzes the same reaction
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lsoenzyme
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