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6 Cards in this Set

  • Front
  • Back

Centrally Acting Skeletal Muscle Relaxants

Clobenzaprine hydrochloride (Flexerill)


Baclofen (Lioresal)


Carisoprodol (Soma)


Methocarbamol (Robaxin)

Benzodiazepines that relax skeletal muscles

Clomazepam (Klonapin)


Diasepam (Valium)


Lorazepam (Ativan)

Centrally Acting Skeletal Muscle Relaxants Adverse Reactions

Drowsiness, dizziness, dry mouth, sedation, urinary retention, hypotension, bradycardia, anaphylaxis, resp depression, coma, laryngospasm, cardio collapse, liver damage



Clobenzaprine hydrochloride (Flexerill) may cause tachycardia

Centrally Acting Skeletal Muscle Relaxants Antidotes

Physostigmine salicylate



Flumazenil for the Benzodiazepines

Direct Acting Antispasmodic Drugs

Working at the Neuromuscular Junction:


- botulinum toxin type A (botox)


- botulinum toxin type B (Myobloc)


Injected directly into the target tissue.



Adverse Reactions:


HA, dysphagia, ptosis, local muscle weakness, pain, muscle tenderness, anaphylaxis, death


Direct Acting Antispasmodic Drugs

Working on Skeletal Muscle:


- dantrolene sodium (Dantrium)



Adverse Reactions:


Muscle weakness, dizziness, drowsiness, dry mouth, tachycardia, erratic blood pressure, diarrhea, hepatic necrosis - estrogen products increase the risk.



No Alcohol, NO CALCIUM CHANNEL BLOCKERS