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50 Cards in this Set

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this is the layer of connective tissue each muscle is surrounded by
epimysium
this is the term for a bundle of muscle fibers
fasiculus or fasicle
this is the connective tissue that surrounds a fascicle
perimysium
within a fasciculus this separates adjacent muscle fibers
endomysium
what is the technical term for the plasma membrane of a muscle cell?
sarcolemma
this is an electrical impulse received or conducted by a muscle cell
action potential
how many nuclei do skeletal muscle cells have?
multiple
what did skeletal muscle's multiple nucleation result from?
embryonic fusion of during development
what did skeletal muscle's multiple nucleation result from?
embryonic fusion of single nucleus cells during development
what are some processes associated with exercise skeletal muscle nuclei are responsible for?
hypertrophy
this is the watery solution found outside the nucleus in muscle cells
sarcoplasm
what does sarcoplasm contain?
energy sources, organelles,
this organelle is the site of aerobic ATP production
mitochondria
this organelle stores calcium and regulates the muscle action process by altering the intracellular calcium concentration
endoplasmic reticulum
this organelle stores calcium and regulates the muscle action process by altering the intracellular calcium concentration
sarcooplasmic reticulum
when does the sarcoplasmic reticulum release calcium into the sarcoplasm
when an action potential passes to the center of the cell through t tubules
these are channels that form from openings in the sarcolemma of the muscle cell
transvers tubules or t tubules
these are columnar protein structures that run parallel to the length of the muscle fiber
myofibrils
what do myofibrils primarily consist of?
myofiliments
what are the two myofiliments?
actin and myosin
this is the thin myofiliment
actin
this is the thick myofilament
myosin
what does each myosin molecule consist of?
head, neck and tail
this portion of myosin is capable of attaching to and pulling on the filament
head
what energy source is used to perform the power stroke of myosin on actin?
hydrolysis of ATP
this connects the head of a myosin filament to the tail
neck
how is the neck of a myosin filament oriented?
so the heads project outwards
how is the neck of a myosin filament oriented?
so the heads project outwards from the ends of the filament
this protein acts to maintain the position of the myosin filament relative to actin
titin
this is what each actin filament is formed from
individual globular or g actin protein
what does each g actin have binding site for?
myosin head
this is what g actin proteins assemble into
strands called f-actin
what are the two proteins that regulate interaction between actin and myosin?
troponin and tropomyosin
this regulatory protein spans the length of seven g actins along the length of the actin filiment
tropomyosin
which regulatory protein lies over the myosin binding sites on actin?
tropomyosin
what is each tropomyosin attatched to at each end?
troponin
what happens when troponin binds with a calcium ion?
causes the movement of tropomyosin away from myosin binding sites on actin
this is the basic contractile unit of muscle
sarcomere
what does the sacromere extend from?
one zline to an adjacen zline
this provides the dark striation of skeletal muscle
a band
this is the area of a band that contains myosin, but not actin
h zone
this is the dark line in the middle of the h zone
m line
what does the m line do?
helps align adjacent myosin filaments
this spans the distance between adjacent myosin filaments and lie partly in each of two sarcomeres
I bands
this give muscle its light striation
I band
where does the communication between the nervous and muscular system occur?
neuromuscular junction
how many muscle fibers are connected to a neuromuscular junction
only 1
what is the most widely accepted theory of muscle action?
sliding filament theory
what is the sequence of events in the sliding filament theory?
1)action potential moves along length of neuron
2)ach is released at axon terminal
3)ach moves across synaptic cleft
4) action potential generated along sarcolemma and into t tubules realeasing calcium
5)calcium binds to troponin causing change in troponin moving tropomyosin
6) muscle in rested state means energized myosin head
7) to release myosin head from actin requires fresh ATP
when is a myosin head in a low energy state?
when it is attached to actin binding site

what causes the release of myosin heads from actin binding sites?
fresh ATP