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26 Cards in this Set

  • Front
  • Back

substances of blood plasma

d

water 91.5 of plasma

liquid portion of blood; solvent and suspending medium; absorbs, transports, and releases heat

plasma proteins 7%

most produced in liver; responsible for blood colloid osmotic pressure; contributor to blood viscosity; transports hormones (steroids), fatty acids and calcium; help regulate blood ph

pp; albumins

smallest/numerous plasma proteins; maintain osmotic pressure and the exchange of fluids across the blood capillary wall

pp: globulin

large proteins (plasma cells produce immunoglobulins)


-help attack viruses and bacteria; alpha and beta globulins transport iron, lipids & fat soluble vitamins

pp; fibrinogen

large protein; blood clotting

other solultes (1.5%)

-

OS; Electrolytes

inorganic salts ; posItive charged cations - Na+. k+, Ca2+, mG2+


Negative charged anions:


CI-, HPO42-, SO42-, HCO3-




FUNCTION: helps maintain osmotic pressure and plays a roll in cell functions

OS: nutrients

products of digestion such as amino acids, glucose, fatty acids, glycerol, vitamins and minerals.




functions: role in cell growth, development, and function

OS: gases

oxygen: o2 - important in cellular function


carbon dioxide: CO2- regulate blood ph


Nitrogen: (N2)- no known function





os: regualtory substances

enzymes - catalyze chemical reactions


hormones- regulate metabolism, growth, and development


vitamins- cofactors in enzymatic reactions

os: waste products

urea,uric acid, creatine, creatinine, bilirubin, ammonia




function: breakdown of protein metabolism carried by the blood to organs of excretion.

hemostasis consists of 3 things

vascular spasm


platelet plug formation


and coagulation

vascular spasm

arteries or arterioles are damaged, smooth muscle walls contract right away (vas spasm)


-reduces blood loss for several hrs

platelet plug formation

clotting factors for platelet plug: ADP; ATP; CA2+ & SEROTONIN


also present are enzymes that produce thromboxane A2, which is a prostaglandin (fibrin


stabilizing factor, strengthens blood clot); lysosomes; some mitochondria;

platelet plug formation continued: platelet derived growth factor: PDGF

A hormone that causes proliferation of vascular endothelial cells, vascular smooth muscle fibers, and fibroblasts to help repair damaged blood vessel.

platlet plug formation step 1

platlets contract and stick to parts of damaged endothelial cells; process is called platelet adhesion

platlet plug step 2

due to adhesion , platlets become activated- they extend many projections that enable them to contact and interact with one another & liberate contents of their vessels; which is called platelet release reaction- liberateeed ADP and thrombazane A2 play a major role by activating nearby platlets



platlet plug step 2 continued

serotonin and thromboxane A2 function as vasoconstrictors, causing and sustaining contraction of vascular smooth muscle , which decreased blood flow through injured vessel

platlet plud 3

the release of adp make area sticky and the newly recurited and acticated paltlets adhere to the orignaly activated platlets

platlet aggregation

gathering of platlets

platllet plg

accumulation of large numbers of platlets form a mass

blood clotting

to clot it needs clotting factors such as calcium ions, inactive enzymes that are synthezied by hepatocytes & released into the blood stream




complex cascade of enzymatic reactions

common pathway

formation of prothrombinase marks the beginning the common pathway

tissue facor

initiates the formation of prothrombinase

clot retraction

once clot formed the ruptured are pf the bv and stops blood loss


- consolidation of the fibrin clot


-as retracts pulls the damaged ends of vessel closer together- decreasing further damage