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17 Cards in this Set
- Front
- Back
- 3rd side (hint)
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What reagent involves a SN2 attack of an alkoxide ion (alcohol) and an alkyl halide? |
Williamson Ether Synthesis 1.NaH (or NaNH2)/THF 2.Alkyl halide (or Tosylate) |
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What reagent changes an alkene to an ether? |
Alkoxymercuration-Demercuration
1. (CF3CO2)2Hg/ whichever 1° alcohol you need 2.NaBH4 (demercuration, removes HgOC(O)F3) Markovnikov's Rule |
Alkoxymercuration-Demercuration |
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An ether undergoes SN1 acidic cleavage when it has what property? |
A with a benzylic, allylic, or 3° carbon. The halide ends up on the more hindered side. |
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An epoxide becomes trans 1,2 alcohol ether due to what reagents? |
ONa/an alcohol (solvent) 1. MgBr/ether 2. H2O/H3O+ (your call) 1.LiAlH4/THF 2. H2O Bases, as they generate H- or have a loose Oxygen somewhere. Always SN2. |
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A thiol (SH-R) becomes a sulfide via what reagents? |
1.NaNH2 2. An alkyl halide |
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A 1° alcohol becomes an aldehyde via what reagent? |
PCC / CH2Cl2 |
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A terminal alkene that goes through oxidative cleavage forms what two products? |
Acetaldehyde (CCHO) and formaldehyde (O=CH2) |
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A terminal alkyne becomes an aldehyde via what process? |
Hydroboration/oxidation 1.BH3/THF 2. H2O2/KOH |
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2° alcohols become ketones via what reagents? |
CrO3/H+ PCC/CH2Cl2 KMnO4/H+ Na2Cr2O7/H+ (sodium dichromate) Oxidizing reagents, essentially. |
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Ozonolysis of an alkene forms what? |
Two ketones. |
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A terminal alkyne becomes a ketone via what reagent? |
HgSO4 H2O/H2SO4 Hydration |
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A benzene gets a ketone added on to it by what reagent? |
An acid chloride (CCO-Cl) AlCl3 |
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An acid chloride (CCO-Cl) become a ketone using what? |
A gilman reagent [ ( /\)2 CuLi/ether ] |
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Aldehydes become carboxylic acids via what reagents? |
CrO3/H+ PCC/CH2Cl2 KMnO4/H+ Na2Cr2O7/H+ (sodium dichromate) Oxidizing reagents, essentially. |
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Ketones become carboxylic acids via what reagents? |
Trick question, they don't. There's no hydrogen to interact with. |
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Both aldehydes and ketones can become a 1,1 diol (geminal diol) via what reagents? |
H3O+/H2O -or- NaOH/H2O Acid or base catalyzed, doesn't matter. |
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Are you amazing? |
Man, hell yeah. |
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