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5 Cards in this Set
- Front
- Back
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what is clonal deletion? |
T cells that do not recognize MHC I protein and most T cells that recognize MHC I protein in conjunction with autoantigens are removed by apoptosis. |
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what are regulatory T cells (Tr cells) |
previously known as suppressor T cells, repress adaptive immune responses and prevent autoimmune diseases. |
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describe further clonal deletion |
B cells with B cell receptors that respons to autoantigens are selectively killed via apoptosis |
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what are cytokines |
are soluble regulatory proteins that act as intercellular signals to direct activites in immune responses |
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what all do cytokines include? |
interleukin (IL's), interferons (IFNs), growth factors, tumor necrosis factors (TNFs) and chemokines |
