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49 Cards in this Set

  • Front
  • Back

Neurology

Study of function and disorders of the nervous tissue

Neurologist

Doctor who practices neurology

2 divisions of nervous system

Central Nervous System and Peripheral Nervous System

Nervous system characteristics

Regulates body activities by responding rapidly using nervous impulses


Effects are short lived, unless repeated


Includes our perceptions, behaviors, memories and initiates all voluntary movements

Nerve

A bundle of hundreds to thousands of axons

Brain

Contains 100 billion neurons

Cranial nerves

Emerge from base of brain. 12 pairs, numbered 1-12.

Spinal Cord

Extends from brain. 100 million neurons.

Spinal Nerves

31 pairs of spinal nerves that emerge from the spinal cord

Ganglia

Contain cell bodies of neurons located outside brain and spinal cord. Closely associated with cranial and spinal nerves.

Enteric plexuses

Extensive networks of neurons located in walls of intestinal tract. Interweaving structures.

Sensory receptors

Dendrites of sensory neurons or separate specialized cells that monitor changes in internal or external environment

Sensory function of the nervous system

Sensory receptors detect many different types of stimuli inside and outside body. Carry sensory info to brain through spinal nerves. Attach at neurons.

Integrative function of the nervous system

When nervous system processes sensory info by analyzing and storing some of it and by making decisions for appropriate responses. Many neurons that participate in integration are interneurons.

Motor function of the nervous system

Elicited motor response to stimulus. Involves motor neurons.

Central Nervous System (CNS)

Brain and Spinal Cord

Peripheral Nervous System (PNS)

Cranial nerves and branches; ganglia; spinal nerves; sensory receptors

Sensory neurons

Head, body wall, viscera, limbs, as well as hearing, vision, taste, and smell, conduct info to CNS.

Motor neurons

Transfer info from CNS to muscles

Autonomic nervous system

Sensory organs, sweat, sexual arousal, fight or flight

Sympathetic nervous system

Fight or flight

Parasympathetic nervous system

Rest and digest

Enteric nervous system

Gut brain. Involuntary control of GI tract. Nerves extend most of length of GI tract.

Neuron

Functional unit of nervous system

Neuroglial cells

Function to surround neurons and hold in place. Supply nutrients and oxygen to insulate between neurons, destroy pathogens, and remove dead neurons.

Cell body of neuron

Single nucleus surrounded by cytoplasm and typical organelles including Nissl bodies.

Axon

Axolemma, axoplasm, axon hillock, initial segment, trigger zone, axon collaterals, axon terminals. Transmission part of neuron. Long thing cylindrical projection. Conducts nerve impulses toward another neuron, muscle gland, or cell.

Dendrites

Little tree. Cell processes. Receptors. Input part of neuron.

Synapse

Site where two neurons meet.

Synaptic end bulbs

Large region at end of axon terminal contain synaptic vesicles and synaptic vesicles store nerve transmitters.

Multi polar neurons

Several dendrites; one axon

Bipolar neurons

Only in retina, olfactory part of brain, inner ear

Unipolar neurons

one process that divides into dendrite and axon

Myelination

Axon is covered by a myelin sheath; increases the speed of nerve inpulses. Produced by oligodendrocytes in the CNS and Schwann cells in the PNS

Grey matter

Unmyelinated

White matter

Myelinated

Ion Channels

When ion channels are open, ions move down concentration gradient towards membrane. Cause change in membrane potential. Movement takes place at various gates.

Leakage channels

Always open, Plasma membranes have more K+ gates than Na+ gates. Voltage gated channels open and respond to change in membrane potential.

Gated channels

Ligand gated. Open and close in response to chemical stimulus from neurotransmitters and hormones.

Mechanically gated channels

Open from mechanical stimulus. Vibration, pressure, tissue stretching.

Resting membrane potential

70 milivolts in resting neuron. Electric charge of resting membrane.

Action potential

A sequence of rapidly occurring events that decrease and reverse the membrane potential till it gets back to resting state.

Synaptic transmission

Neurons communicating with other neurons or with effectors by a series of events. Happens at synapses.

Steps of synaptic transmission

1. Nerve impulse arrives at synaptic end bulb of a presynaptic neuron through the axon


2. Impulse opens Ca2+ channels in the synaptic end bulbs


3. Increase in Ca2+ triggers exocytosis of synaptic vesicles, releasing neurotransmitters into the synaptic cleft


4. Neurotransmitters bind to neurotransmitter receptors in the post synaptic neuron's plasma membrane


5. Ion channels open as a result of step 4


6. Voltage of neuron changes; impulse continues or the effect happens

Absolute refractory period

Time in which the neuron can't generate new action potential

Relative refractory period

When suprathreshold stimulus generates action potential

Neurapraxia

Loss of conductivity, but axon stays intact and recovery is complete

Axonotmesis

Degeneration of axon distal to the lesion; connective tissue is intact

Neurotmesis

Same as axonotmesis, but connective tissue is damaged