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94 Cards in this Set

  • Front
  • Back

The autonomic nervous system consists of motor neurons that

innervate smooth, cardiac muscle and glands.

The ANS consists of motor neurons that opperate via

subconscious control

What are the three ways the autonomic nervous system differs from the somatic nervous system

-Effectors
-Efferent Pathways
-Tangent organ responses

What are the effectors of the SNS

skeletal muscles

What are the effectors of the ANS (3)

Caridiac muscles, smooth muscles and glands

Axons of the ANS are a ______-______ chain

Two neuron

What is the first neruron of the ANS two neuron chain?

preganglionic

What is the second neuron of the ANS two neuron chain?

postganglionic

preganglionic neurons are...

lightly myelinated

postganglionic neurons extend...

to an effector organ

All somatic motor neurons release _______, which has an ________ effect

-Acetylcholine
-Excitatory

Which neuron release ACh, pre or postganglionic?

Preganglionic

What do postganglionic neurons release and what is the effect?

-norepinephrine or ACh
-either excitatory or inhibitory

ANS effect on the target organ


is dependent upon the ________ _________ and the _________ ___________ of the effector.

-neurotransmitter released
-receptor type

What are the two divisions of the ANS?

  1. sympathetic
  2. parasympathetic

What does the sympathetic division of the ANS do?

mobilizes the body during extreme situations (fright/flight)

What does the parasympathetic division of the ANS do?

performs maintenance activities and conserves body energy (rest/digest)

Which division of the ANS deals with the "D" activities, and what are these?

-Parasympathetic
-digestion, defecation, and diuresis (Rest - Digest)

What division of the ANS deals with the "A" activities, and what are these?

-Sympathetic
-exercise, excitement, emergency, and embarrassment

Which division of the ANS is the "Fight or Flight" division?

-Sympathetic

Sympathetic Division: Origin of Neurons

-Thoracolumbar region of the spinal cord


T1 - L2

Sympathetic Division: Length of Neurons

-Short preganglionic and long postganglionic

Sympathetic Division: Location of Ganglia

Close to the spinal cord


*Sympathetic Trunk Ganglia*

Parasympathetic Divison: Origin of Neurons

  1. S2 - S4
  2. Cranial Nerves III, VII, IX, X

(craniosacral)

Parasympathetic Divison: Length of Neurons

Long preganglionic and short postganglionic

Parasympathetic Divison: Location of Ganglia

In the terminal ganglia, which are near or within the effector organs.

What is the ganglion and effector organ of the occulomotor (III) nerve?

-Ciliary
-Eye

Which cranial nerve has the ganglion located within the walls of the target organs and what is the effector organs?

-Vagus (X)
-Heart, lungs and most visceral organs

What are the effector organs in the sacral division of the parasympathetic system?

-Large intestine, urinary bladder, ureters, and reproductive organs

Sympathetic neurons produce the _______ ______ of the spinal cord.

-Lateral Horns

In a sympathetic outflow, preganglionic fibers pass through the ______ ________ _______ and _______ in the sympathetic trunk(paravertebral) ganglia.

-White rami communicans
-Synapses

Nerves from the T5-L2 form ________ nerves and synapses with ________ ganglia

-Splanchnic
-collateral

Postganglionic neurons innervate

numerous organs of the body

What ganglia forms part of the sympathetic trunk or chain?

-Paravertebral ganglia

Postganglionic axons enter the _______ rami via the ______ rami communicans

-ventral
-gray

Rami communicans are associated only with the ________ ________

-sympathetic division

Nerves of the thoracic _______ nerve pass directly to the _______ _______

-Splanchnic
-Adrenal Medulla

Upon stimulation, medullary cells secrete the hormones ________ and ________ into the blood.

-norpinephrine
-epinephrine

In visceral reflexes they are pathways are always __________ .

-polysynaptic

Visceral Reflexes: Afferent fibers are found in _______ and ________ nerves

-Spinal and autonomic

Pain stimuli arising from the _______ are perceived as _______ in origin.

-Viscera
-Somatic

Visceral pain afferents travel along the same pathways as _______ ______ fibers

-Somatic pain

What are the two major neurotransmitters of the ANS?

-Acetylcholine (ACh)
-Norepinephrine (NE)

ACh is released by all ________ neurons and all ________ ______ neurons.

-preganglionic
-parasympathetic postganglionic

Cholinergic Neurons release...

ACh

Adrenergic Neurons release...

NE in sympathetic postganglionic neurons.

Neurotransmitters effects can be ______ or ______ depending upon the receptor type.

-excitatory or inhibitory

The two types of receptors that bind ACh are...

-nicotinic and muscarinic

Nicotinic and muscarinic are named after drugs that

bind to them and mimic ACh effects

Nicotinic receptors are found on (3)

-neuromuscular junctions
-postganglionic neurons
-hormone-producing cells of the adrenal medulla

The effect of ACh binded to nicotinic receptors is always...

-stimulatory

The effect of ACh binding depends on the

-receptor type of the target organ

The two types of adrenergic receptors are

alpha and beta

Alpha 1 and Beta 1 receptors generally...

"excite things"

Alpha 2 and Beta 2 receptors generally...

"relax things"

Effects of Drugs: Atropine

-blocks parasympathetic effects

Effects of Drugs: Neostigmine

-inhibits acetylcholinesterase and is used to treat myasthenia gravis

Effects of Drugs: Tricyclic antidepressants

prolong the activity of NE on postsynaptic membranes

Effects of Drugs: Beta-blockers

attach mainly to Beta receptors and reduce heart rate and prevent arrhythmias

Interaction of the autonomic divisions results in ______ _______ that precisely control visceral activity

-dynamic antagonisms

Sympathetic Neurons

-increase heart and respiratory rates, and inhibit digestion and elimination

Parasympathetic Neurons

-decrease heart and respiratory rates, and allow for digestion and the discarding of wastes

The sympathetic division controls blood pressure and keeps the blood vessels in a

continual state of partial constriction

Whic type of drugs interfere with vasomotor fibers and are used to treat hypertension?

Alpha-Blocker

Drug that block parasympathetic responses

-atropine

Which 4 items are only innervated by the sympathetic system?

  1. adrenal medulla
  2. sweat glands
  3. arrector pili muscles
  4. most blood vessels

What three aspects does the sympathetic division control

-thermoregulatory responses to hear
-release of renin from kindeys
-metabolic effects

The parasympathetic division exerts

short-lived, highly localized control

The sympathetic divison exerts

long-lasting, diffuse effects

Sympathetic activation is long-lasting because NE is

inactivated slower than ACh

Effects of: Alpha 1 receptors (3)

  1. Vasoconstriction (vessels of non-exercising tissues
  2. Pupil Dilation
  3. Sphincter constriction (GI & Urinary

Effects of: Alpha 2 receptors (1)

Increased blood glucose

Effects of: Beta 1 receptors (4)

  1. Heart muscle (increased contractility)
  2. SA Node-regulates HR (Increased HR)
  3. Adipocytes (mobilize fat - used for energy)
  4. Kidneys (vasoconstriction)

Effects of: Beta 2 receptors (3)

  1. Blood vessels of exercising tissues (vasodilation)
  2. Bladder & GI organs (relax smooth muscle & inhibit urination/digestion)
  3. Smooth muscle of airways (bronchodilation)

The _____ rami communicans are unmyelinated.

Gray

Name the 3 autonomic plexuses..

  1. Cardiac Plexus
  2. Pulmonary Plexus
  3. Aortic Plexus

This autonomic plexus is found in the base of the heart plus great vessels of the heart.

Cardiac Plexus

The pulmonary plexus is found...

Posterior to the lungs

The _____ plexus is found surrounding the aorta.

Aortic Plexus

______ cells reside within the adrenal medullae.

Chromaffin Cells

Chromaffin cells secrete _______.

Catecholamines

Name the 3 catecholamines:

  1. Epinepinephrine
  2. Norepinephrine
  3. Dopamine

_____ and ______ are types of cholinergic receptors.

Nicotinic and Muscarinic

Muscarinic receptors are present in...

  1. Smooth muscle
  2. Cardiac muscle
  3. Glands

A drug that binds to and activates a receptor is considered an ______.

Agonist

An agonist mimics...

..the natural effect of the neurotransmitter or hormone.

An example of an agonist drug is ________.

Phenylephrine

Phenylephrine activates...

...alpha 1 receptors - cause vasoconstriction of blood vessels to nasal mucosa.


(used in cold medicines)

An ________ drug binds to and blocks a receptor.

Antagonist

An example of an antagonist drug is________.

Tamoxifen

Tamoxifen binds to ....

..estrogen receptors in breast tumors which prevents estrogen from binding and serving as "food" for the breast tumor.

Organ systems that are innervated by both sympathetic and parasympathetic systems are considered _______ _______.

Dual Innervated

Name an example of autonomic reflex:

Pupillary light reflex

Integrating center for reflexes are the ________ and _______ _______.

Hypothalamus and brain stem