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20 Cards in this Set

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  • Back

Amphetamines

A class of stimulant drugs that include amphetamine sulfate and all of its drug derivatives

Analeptics

-CNS stimulants


-effects on Brainstem and Spinal Cord


-increase responsiveness to external stimuli


-increase Respiration



Anorexiants

Drugs that control or suppress appitite

ADHD

A syndrome characterized by difficulty in concentration or hyperactive behavior.




(affects children,adolescents,adults)

Cataplexy

-Abrupt attacks of MM weakness & hypotonia (floppy mm)




-Triggered by an emotional stimulus such as joy, laughter, anger, fear or surprise

CNS Stimulants

Drugs that stimulate Brain or Spinal Cord

Ergot Alkaloids

-Drugs that constric blood vessels in brain


-Provides certain migraine pain relief (used to be the main drug for migraines)





Migraine

-Reoccuring painful H/A


-Pulsatile or Throbbing (common to be unilateral but may be bilateral)


-incapacitating pain


-photophobia (avoid light)


-phonophobia (avoid sound)


-Lasts 4 -72 hrs


-Begin after 10 y.o--- Peak between mid 20s and early 40s ----fade after 50s


-inherited

Narcolepsy

-incurable neurologic conditon


-Sudden "Sleep Attacks"


-cataplexy (Acute sudden mm skeletal weakness)


-visual or auditory hallucinations @ onset of sleep


-Usually associated w/ strong emotions (ie., joy, anger)


-Commonly buckle at the knee & PA falls.


-(over half the PA diagnosed experience migraines)

Serotonin Receptor Agonist

CNS stimulants currently used as first line therapy for trting Migraine H/A


aka. selective serotonin receptor agonist OR aka. triptans


- stimulates receptors in cerebral arteries, causing vasoconstriction which reduce or eliminates H/A symptoms


- Can trt H/A that has already started... This is known as "Abortive" drug therapy-

Sympathomimetic Drugs

CNS stimulants like NORADRENERGIC drugs (norepinephrine) and sometimes (Dopamine)




acts similarly (mimics) those of the sympathetic nervous system (fight or flight)

CNS Excitatory Neurotransmitters

Dopamine (Dopaminergic drugs)




Norepinephrine (Adrenergic drugs)




Serotonin (Serotonergic drugs)

Dopamin is a metabolic precursor to

Norpinephrine.




which is also a neurotransmitter to the sympathetic nervous system

Adrenergic Drugs mimic the actions of

Sympathetic Nervous System






sometimes aka. sympathomimetic drugs

ADHD

-Most common psychiatric disorder in school age children.


-Boys are 2 to 9 times affected than girls


-Symptoms: no attention span, or hyperactivity & impulsivity


- Drug Trt for child and adult are same

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Analeptic-Responsive Repspiratory Depression Syndroms

-Neonatal Apnea (preme babies stop breathing for a short time)


-Bronchopulmonary dysplasia (chronic lung dz) (infants -> prolonged use of mechanical ventilator)


-Post Anesthetic Respiratory Depression (post general anesthesia)




*Drugs for these conditions are*


-Theophylline -Caffeine


-Aminophylline -Doxapram (dopram)

Drugs for ADHD & Narcolepsy

Amphetamines: methylphendate




Non Amphetamine stimulant: premoline & modafinil




Nonstimulant drug for ADHD: Atomoxetine (low incidence of insomnia & low abuse potential)




Lisdexamfetamine (Vyvanse) Prodrug for dextroamphetamine

Amphetamines Actions on the CNS and Resp.

CNS:


-Stimulates mental alertness


-euphoria


-decrease fatigue


RESP:


-Relax bronchial smooth mm


-Increase resp


-Dilates pulmonary arteries

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