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169 Cards in this Set

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What are the three general functions of the nervous system?
Sensation, Integration & Response, Action
SIR
When senses change inside and outside of the body this is known as:
Sensation
After senses change inside and outside of the body these changes must be interpreted. This process is known as:
Integration
Senses change inside and outside of the body, and then they become interpretted. After the become interpreted they must respond to interpretation by initiatizing action in the form of muscular contractions or glandular secretions. This is known as:
Response/Action
What are the 2 principal (anatomic) divisions of the nervous system?
Central Nervous System & Peripheral Nervous System
The control center for the entire nervous system.
Central Nervous System
Consists of the Brain & Spinal Cord.
Central Nervous System
Well protected; Incased in the skull and vertebral column
Central Nervous System
Connects to the CNS to receptors, muscles & glands
Peripheral Nervous System
What are the two divisions of the PNS?
Afferent & Efferent
Conveys impulses from receptors to CNS --> sensory neurons.
Afferent division
Note: A for afferent means attract.
Conveys impulses away from CNS to periphery --> motor neurons.
Efferent division
Note: E for efferent means exit.
A third type of neuron that connects the afferent to the efferent neurons. Present only in the CNS.
Interneurons
Interneurons are only present in that:
CNS
(outputs; motor neurons) Can be further divided into Somatic & Autonomic nervous systems.
Efferent Nervous System
The Efferent Nervous System (Part of the PNS) is branched into which two nervous systems?
Somatic & Autonomic Nervous Systems
(PNS) (ENS) The "manual" or "conscious" nervous system. Efferent neurons that conduct impulses from the CNS to skeletal muscles. (Voluntary)
Somatic Nervous System
Efferent neurons that conduct impulses from the CNS to skeletal muscles.
Somatic Nervous System
The Somatic Nervous System Is (VOLUNTARY/INVOLUNTARY)
VOLUNTARY
(PNS) (ENS) Think "Automatic" or "Unconscious." Efferent neurons that convey impulses from CNS to smooth muscle, cardiac muscle and glands. (Generally the visceral tissues and organs) (Involuntary)
Autonomic Nervous System
Efferent neurons that convey impulses from CNS to smooth muscle, cardiac. Muscle & glands. (Generally the visceral tissues and organs)
Autonomic Nervous System
The Autonomic Nervous System is (VOLUNTARY/INVOLUNTARY)
INVOLUNTARY
The Autonomic Nervous system is divided into what two nervous systems?
Sympathetic NS & Parasympathetic NS
Stimulation of this system increases heart rate.
Sympathetic NS
Stimulation of this system decreases heart rate.
Parasympathetic
The functional unit in the nervous system.
Neuron
What are the 3 distinct parts of a neuron?
Cell body, Dendrite & an Axon
Neuron's well-defined nucleus surrounded by granular cytoplasm.
Cell Body
Contains the typical cellular organelles in a neuron.
Cell Body
Site of synthesis of the nerve cell's products (hormones, neurotransmitters, etc.)
Cell Body
Similar to the rough ER of other cells, this is the attachment for ribosomes found exclusively in nerve cell bodies.
Nissl bodies
Highly branched, thick, tapering extensions of cytoplasm of cell body.
Dendrite
How many dendrites can be in the neuron?
As few as one or as many as thousands.
Part of the neuron that conducts impulses toward cell body.
Dendrite
A single structure in the neuron.
Axon
Highly specialized, a long thin process within the neuron.
Axon
At the origin of an axon is an enlarged segment that iniates AP's. This is known as the:
Axon Hillock
The axon may branch out, away from the cell body from a single process. These branches are called ________________.
Collaterals
An enlargement of the branched distal end of the axon that forms part of the synapse.
Synaptic Knob
The small space between the synaptic knob and the receptive area of the receiving cell, across which neurotransmitter diffuses.
Synaptic Cleft
Part of the neuron that conducts impulses away from the cell body.
Axon
Fine threads that extend into the axon and are part of the cytoplasm (part of cytoskeleton)
Neurofibrils
The whole processes of neurons, bundles of which make up a nerve.
Nerve fibers
Many Schwann cells wrapped around an axon with spaces in between and facilitates high speed transmission of impulses.
Myelin Sheath
When a single Schwann cell envelops, along its periphery, the axons of the nerve fibers it serves. "Sheath of Schwann."
Neurilemma
Note: Remember that "lemma" means "husk" or "outer layer"
What are the two types of intracellular systems for the axonal transport of synthesized materials from the cell body?
Axoplasmic Flow & Axoplasmic Transport
System for the axonal transport of synthesized materials from the cell body. This is undirectional-- only flows in one direction, which is away from the cell body. This is a slow process.
Axoplasmic Flow
System for the axonal transport of synthesized materials from the cell body. Conveys materials in both directions. Faster process.
Axoplasmic Transport
The reverse process of axoplasmic transport is:
Retrograde Transport
The route taken by certain viruses and bacteria which can damage the CNS. (Herpes and Rapies viruses and Tetanus bacterium)
Retrograde Transport
Covers many of the nerve fibers in the PNS.
Myelin Sheath
Multilayered, white, phospholipid, segmented covering.
Myelin Sheath
Contain the myelin sheath
Myelinated Nerve Fibers
Lack the myelin sheath
Non-Myelinated Nerve Fibers
Function is to increase the speed with which an impulse is conducted along a fiber.
Myelin Sheath
Are Scwann Cells nervous tissue?
NO
Flattened, NON-NEURONAL CELLS which produce the myelin sheath.
Schwann Cells
These encircle the axon until its ends meet and overlap.
Schwann Cells
These wind around the axon many times, pushing the nucleus to cell's periphery and becomes many layered.
Schwann Cells
Schwann Cells wind around the _______.
Axon
The small space between the Schwann cells is the: ___________________
node of Ranvier
The Sheath of the schwann cells
Neurilemma
Peripheral nucleated cytoplasmic layer of the schwann cell.
Neurilemma
Assist in regeneration of injured axons (nerve fibers)
Neurilemma
(TRUE/FALSE) In Neurilemma, if a damaged cell body dies it is replaced with a new cell body.
FALSE
Unmyelinated gaps between the segments of the myelin sheath
Nodes of Ranvier
These are enclosed by Schwann cells, however, there are no multiple wrappings. Which means that they may have a neurilemma, but not be myelinated, because there are no multiple wrappings of Schwann cells.
Unmyelinated Nerve Fibers
No multiple wrappings
Unmyelinated Nerve Fibers
Contains myelinated and unmyelinated fibers as well.
CNS
Myelination is produced by:
a different cell type in the CNS
What produces myelination in the CNS?
Oligodendrocytes
The CNS has ____________________ instead of Schwann cells.
Oligodendrocytes
Neurons that have only teo processes, one on either end.
Bipolar
Neurons that have only a single process and are found in ganglia. The process branches and one is associated with a body part and the other enters the CNS.
Unipolar
Neurons that have many processes arising from their cell bodies with only one being an axon, most of these are in the CNS.
Multipolar
Most of the Multipolar neurons are found in the:
CNS
What are the three structural characteristics of neurons?
Bipolar, Unipolar & Multipolar
BUM
What are the three functional characteristics of neurons?
Sensory, Interneurons & Motor neurons
SIM
These neurons ccarry impulses from the peripheral body parts to the CNS.
Sensory neurons
Also called association or internuncial neruons. Found within the brain or spinal cord, are multipolar, and form links between the other neurons.
Interneurons
Neurons found within the brain or spinal cord. Multipolar. Form links between other neurons.
Interneurons
(TRUE/FALSE) Interneurons are unipolar.
FALSE; multipolar
Multipolar neurons that carry impulses out of the brain or spinal cord to effectors, like muscles or glands.
Motor Neurons
(TRUE/FALSE) Most neurons of the somatic system are voluntary and are consciously controlled.
TRUE
Support cells in the CNS
Glial Cells
Note: Glia means glue, and while we discuss glial cells as being in the CNS, they have their functional counterpart in the PNS in the form of Schwann cells)
These cells provide physical support (including the production of the myelin sheath), protection, nourish neurons and prevent contact between neurons, except at particular cites providing electrochemical insulation.
Glial Cells
Phagocytosis occurs in the:
Glial Cell
The immune component of nerve tissue.
Phagocytosis
(Phagocytosis) The ___________________ prevents WBC's and some antibodies from entering into nervous tissue.
Blood-brain barrier
(Neuroglial Cells) The function of this cell is in the formation of myelin in the CNS.
Oligodendrocytes
(Neuroglial Cells) Differ from Schwann cells in that they form a number of processes (cell extensions) to provide myelin on seceral different axons at the same time.
Oligodendrocytes
(Neuroglial Cells) Provide myelin on several different axons at the same time.
Oligodendrocytes
(Neuroglial Cells) Star-shaped cells which provide structural support for neurons.
Astrocytes
(Neuroglial Cells) Commonly found between axons and blood vessels.
Astrocytes
(Neuroglial Cells) Astrocytes are commonly found between _______________ & _________________.
Axons & Blood vessels
(Neuroglial Cells) May have a nutritive function involving the transport of substances from blood. Vessels to neurons. Remember that neurons have a very high MR.
Astrocytes
(Neuroglial Cells) Phagocytize bacterial cells and cellular debris (an immune type cell)
Microglia
(TRUE/FALSE) Microglia conduct nerve impulses.
FALSE THEY DO NOT!
Cuboidal cells that line the open spaces in the brain, the ventricles.
Epedymal Cells
Epedymal cells are cuboidal cells that line the open spaces in the brain. These open spaces are known as:
Ventricles
(Neuroglial Cells) Form a one-cell thick "epithelial-like" membrane.
Ependymal Cells
(Neuroglial Cells) Line the central canal that goes down the center of the spinal cord.
Ependymal Cells
(TRUE/FALSE) Only neurons carry electrical impulses (chemoelectric) to transmit messages.
TRUE
Only _________ carry electrical impulses (chemoelectric) to transmit messages.
neurons
Only neurons carry _________________ (chemoelectric) to transmit messages.
electrical impulses
Only neurons carry electrical impulses (_________) to transmit messages.
chemoelectric
Only neurons carry electrical impulses (chemoelectric) to __________________.
transmit messages
Impulses must be carried along ____________. (axons and dendrites)
Nerve fibers
Impulses must be carried along nerve fibers (______________ & ____________)
Axons & Dendrites
Impulses must be carried to ________________. (synaptic transmission)
other neurons
Impulses must be carried to other neurons (_______________________)
Synaptic Transmission
What are the two different types of neural transmission?
Nerve Impulse Conduction & Synaptic Transmission
A chemoelectric event over a significant distance. Within a single neuron.
Nerve impulse conduction
A chemical event over a relatively short distance. --Between neurons that are adjacent in some fashion. (Axon to Dendrite)
Synaptic Transmission
Interneuronal communication, or how meurons get their message across -- the chemical connection.
The Synapse
The Synapse must involve what three things?
Pre-synaptic cell, Post-synaptic cell and a Molecular/Chemical Neurotransmitter.
PPM/CN
This must involve a pre-synaptic cell, a post synaptic cell and a molecular/chemical neurotransmitter.
The Synapse
What lies between the pre- and post-synaptic cell membranes (across which NT diffuses)
Synaptic Cleft
Between the _____ & _____________ cell membranes is a synaptic cleft across which NT diffuses.
Pre- & Post-synaptic
The synaptic cleft between the pre- & post- synaptic membranes (across which NT diffuses) is about _____-_______ nanometers, there is no direct cellular contact.
20-25
(TRUE/FALSE) There is direct intracellular contact in the Synaptic Cleft.
FALSE
The recieving cell in the synapse may be a _________, gland cell, or another nerve cell.
muscle cell
The recieving cell in the synapse may be a muscle cell, __________ or another nerve cell.
gland cell
The recieving cell in the synapse may be a muscle cell, gland cell or another __________ cell.
nerve
The recieving cell in the synapse may be a ____________, ________________ or another _____________.
muscle cell; gland cell; nerve cell
Neuron with axonal terminals that form a synapse with another neuron or other excitable cell.
Presynaptic neuron
The membrane from which the neurotransmitter is released.
Presynaptic Membrane
Neuron on the opposite side, or recieving side and has receptor sites for the neurotransmitter.
Postsynaptic Neuron
Membrane where the NT is recieved
Post-Synaptic Membrane
(Points of interconnection of pre-and post- synaptic cells) When an axon forms a synapse between itself and a dendrite it is called:
Axodendritic synapses
(Points of interconnection of pre-and post- synaptic cells) When the axon forms a synapse between itself and the cell body.
Axosomatic synapses
(Points of interconnection of pre-and post- synaptic cells) When the axon forms a synapse between itself and another axon.
Axoaxonic synapses
(Points of interconnection of pre-and post- synaptic cells) If a synapse is formed with a muscle it is called a(n):
Neuromuscular junction
(Points of interconnection of pre-and post- synaptic cells) If a synapse is formed with a gland it is called a(n):
Neuroglandular junction
What does NT stand for?
Neurotransmitters
Conduction is by the means of ________________.
NEUROTRANSMITTERS
___________ is by the means of NEUROTRANSMITTERS.
Conduction
(TRUE/FALSE) Action potentials carried along nerve fiber cross the synaptic cleft.
FALSE
(TRUE/FALSE) Action potentials carried along nerve fiber cannot cross the synaptic cleft.
TRUE
________________ carried along nerve fiber cannot cross the synaptic cleft.
Action potential
Action potential carried along nerve fiber cannot cross the _____________.
synaptic cleft
Why is action potential carried along nerve fiber unable to cross the synaptic cleft?
Because the cleft is too broad for such a weak current to travel across.
The impulses of action potential are transmitted across the synaptic cleft by __________________.
chemical messengers called NT
The impulse of _____________________ are transmitted across the synaptic cleft by chemical messengers called NT.
Action potential
Neurotransmitters are synthesized in an axon and stored in vesicles in an enlarged region at the tip of the axon terminal called the synaptic knob, or bouton. This process is known as
Synaptic Transmission
In synaptic transmission neurotransmitters are synthesized in an _____________ and stored into ___________ in an enlarged region at the tip of the axon terminal called the synaptic knob, or bouton.
Axon; Vesicles
In Synaptic Transmission neurotransmitters are synthesized in an axon and stored in vesicles in an enlarged region at the tip of the axon terminal called the __________________ or _____________.
Synaptic Knob or Bouton
(Synaptic Transmission) NT is stored in these synaptic vesicles until the _______________________ arrives.
Action Potential (AP)
(Synaptic Transmission) The electrical impulse of the AP increases the permeability of the ______________ membrane to Ca++ ions.
Presynaptic
(Synaptic Transmission) The electrical impulse of the AP increases the permeability of the presynaptic membrane to _________________.
Ca++ ions
(Synaptic Transmission) When the _____ reaches the synaptic knob, this electrical stimulation causes the vesicles to migrate to and fuse with, the presynaptic membrane and release their contents, usually a few hundred vesicles, into the synaptic cleft by the process of EXOCYTOSIS.
AP
When the AP reaches the ____________, this electrical stimulation causes the vesicles to migrate and fuse with, the presynaptic membrane and release their contents, usually a few hundred vesicles into the synaptic cleft by the process of EXOCYTOSIS.
synaptic knob
When the AP reaches the synaptic knob, this electrical stimulation causes the ______________ to migrate and fuse with, the presynaptic membrane and release their contents, usually a few hundred vesicles, into the synaptic cleft by the process of EXOCYTOSIS.
vesicles
When the AP reaches the synaptic knob, this electrical stimulation causes the vesicles to migrate and ______ with, the presynaptic membrane and release their contents, usually a few hundred thousand vesicles, into the synaptic cleft by the process of EXOCYTOSIS.
fuse
When the AP reaches the synaptic knob, this electrical stimulation causes the vesicles to migrate and fuse with the ___________________, and release their contents, usually a few hundred vesicles, into the synaptic cleft by the process of EXOCYTOSIS.
presynaptic membrane
The process in which the AP reaches the synaptic knob, and this electrical stimulation causes the vesicles to migrate and fuse with the presynaptic membrane and release their contents, usually a few hundred vesicles into the synaptic cleft.
EXOCYTOSIS
In Exocytosis, the amount of NT that is released is directly related to _______________ that enters the synaptic knowb
the amount of Ca++ ions
In Exocytosis, the amount of Ca++ ions that enters the synaptic knob are directly related to the _______________ that is released.
amount of NT
(Synaptic Transmission) NT molecules ________ across the cleft and bind with ____________ on the post synaptic knob.
diffuse; specific receptors
(Synaptic Transmission) NT molecules diffuse across the cleft and bind with _______________ on the post synaptic knob.
specific receptors
(Synaptic Transmission) NT molecules ______ across the cleft and bind with specific receptors on the post-synaptic membrane.
diffuse
(Synaptic Transmission) The receptor molecule specifically recognizes a _______ and elicit a specific cellular response.
chemical
(Synaptic Transmission) The receptor molecule specifically recognizes a chemical and __________________.
elicit a specific cellular response
Comination of NT's with receptors causes changes in the permeability of the post-synaptic membrane. (the membrane becomes more permeable to some ions-->the ion channels are open)
Receptor-neurotransmitter Interaction
These are chemically gated channels since they require interaction with a neurotransmitter or hormone (chemical) in order to open
Receptor-neurotransmitter Interaction
Increased Na+ permeability leads to what effect? (reduces membrane potential)
Excitatory effect
The Excitatory effect (reduces membrane potential) is caused by:
Increased Na+ permeability
Increased Cl- permeabilty leads to what effect? (increases membrane)
Inhibitory effect
The Inhibitory effect (increases membrane) is caused by:
Increase in Cl-