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45 Cards in this Set

  • Front
  • Back
organ
Two or more tissues grouped together and performing specialized functio
. The largest organ(s) in the body is (are) the
skin
integumentary system
The skin and its various structures make
Skin and Its Tissues (functions)
Composed of several tissue types
Maintains homeostasis
Protective covering
Retards water loss
Regulates body temperature
Houses sensory receptors
Contains immune system cells
Synthesizes chemicals
Excretes small amounts of wastes
Skin Cells
Help produce Vitamin D needed for normal bone and tooth development

Some cells (keratinocytes) produce substances that stimulate development of some white blood cells
Layers of Skin
Epidermis
Dermis
Subcutaneous layer
A.k.a hypodermis
Beneath dermis
Epidermis 6 characteristics
Lacks blood vessels
Keratinized
Thickest on palms and soles (0.8-1.4mm)
Melanocytes provide melanin
Rests on basement membrane
Stratified squamous epithelia
There are five (5) layers of the epidermis
Stratum corneum
Stratum lucidum (only in thick skin – palms, soles)
Stratum granulosum
Stratum spinosum
Stratum basale
Explain what happens to epidermal cells as they undergo keratinization
As new cells in the epidermis are produced, they are pushed upwards from the basement membrane towards the outside of the skin. As they get further from their nutrient source they die. As the process occurs, the maturing cells undergo a hardening process (keratinization) during which the cytoplasm develops strands of tough, fibrous, waterproof proteins called keratin. These dead cells form many tough, waterproof layers. These dead cells are rubbed away as newer cells replace them.
Stratum coronea where and what
Outermost layer
many layers of keratinized, dead epithelial cells that are flattened and nonnucleated
stratum lucidum where and what
Between the statum corneum and stratum granulosum on soles and palms
cells appear clear;nuclei,organelles and membranes are no longer visible
Startum granulosum beneath stratum corneum
three to five layers of flattened granular cells that contain shrunken fibers of keratin and shriveled nuclei
Statum spinosum
beneath the stratum granulosum many layers of cells with centrally located large oval nuclei and developing fibers of keratin: cells becoming flattened.
Startum basal deepest layer
single row of cubudiol or columnar cells that divide and grow this layer includes melanocytes.
Epidermis Genetic Factors
Varying amounts of melanin
Varying size of melanin granules
Albinos lack melanin
malanocytes
specialized cells that produce dark pigment which provides skin color.
Physiological Factors
epidermis
Dilation of dermal blood vessels
Constriction of dermal blood vessels
Accumulation of carotene
Jaundice
Environmental Factors
epidermis
Sunlight
UV light from sunlamps
X-rays
Darkens melanin
Dermis characteristics (10)
On average 1.0-2.0mm thick
Contains dermal papillae
Binds epidermis to underlying tissues
Irregular dense connective tissue
Muscle cells
Nerve cell processes
Specialized sensory receptors
Blood vessels
Hair follicles
Glands
Describe three physiological factors that affect skin color
The dermal blood supply affects skin color. For example, when the blood is well oxygenated, the hemoglobin makes the skin appear pinkish. When the blood is not well oxygenated, the hemoglobin is darker and the skin appears bluish (cyanosis). In the presence of high levels of carotene in the blood, the skin may exhibit a yellowish cast. Illnesses may also affect skin color.
Papillary layer (dermis)
Thin
Superficial
Dermal papillae here
Reticular layer
(dermis)
80% of dermis
Cleavage, tension or Langer’s lines are here
Subcutaneous Layer
A.k.a hypodermis
Loose connective tissue and Adipose tissue
Insulates
Major blood vessels present
Accessory Structures of the Skin
Accessory structures of the skin originate from the epidermis and include:
Hair follicles
Nails
Skin glands
Hair Follicles
Epidermal cells
Tube-like depression
Extends into dermis
Three (3) parts:
Hair root
Hair shaft
Hair papilla
. Distinguish between a hair and a hair follicle
Hair is present on all skin surfaces except the palms, soles, lips, nipples, and various parts of the external reproductive organs. A hair follicle is a group of epidermal cells at the base of a tube-like depression. The root of the hair occupies this follicle. As these cells divide and grow, they are pushed toward the surface and undergo keratinization and subsequent cell death. The cells’ remains form the structure of a developing hair whose shaft extends away from the skin surface. This shaft is called the hair.
Review how hair color is determined
Genes that direct the type and amount of pigment produced by epidermal melanocytes determine hair color.
Bright red hair contains an iron pigment (trichosiderin) that does not occur in hair of any other color. Gray hair is the result of a mixture of pigmented and unpigmented hair.
What kind melanin produce brown/black hair and what kind of melanin produce blonde hair.
eumelanin-black
phenomelanin-blonde
Nails
contain a lunula, nail bed , and plate
Sebaceous Glands
Usually associated with hair follicles
Holocrine glands
Secrete sebum (oil)
Absent on palms and soles
. Explain the function of sebaceous glands
Sebaceous glands contain groups of specialized epithelial cells and are usually associated with hair follicles. They are holocrine glands that secrete an oily substance called sebum (a mixture of fatty materials and cellular debris) that serve to keep the hair and skin soft, pliable, and relatively waterproof.
eccrine sweat glands
abundant sweat glands that are odorless that lower body temprature
apocrine sweatglands
less numerous that eccorine that devlop orders, used wet skin during pain,fear,emotional upset and sexual arrousal
ceruminous glands
secrete earwax
mamary glands
secret milk in the breast.
Regulation of Body Temperature why is it important
Regulation of body temperature is vitally important because even slight shifts can disrupt metabolic reactions.
The primary means of heat loss is
radiation
Also there is conduction, convection and evaporation
Problems in Temperature Regulation
Hyperthermia – abnormally high body temperature
Hypothermia – abnormally low body temperature
Healing of Wounds and Burns
Inflammation is a normal response to injury or stress.
Blood vessels in affected tissues dilate and become more permeable, allowing fluids to leak into the damaged tissues.
Inflammed skin may become:
Reddened
Swollen
Warm
Painful
First degree burn
First degree burn – superficial, partial-thickness (dermis superficial)
Second degree burn
Second degree burn – deep, partial-thickness detroys epidermis and some dermis
Third degree burn
full thickness destroys epidermis, dermis and the accessory structures of the skin
Autograft
replacement from another part of ones own skin
Homograft
replacement from another persons skins
. Discuss three effects of aging on skin.
Aging skin affects appearance as “age spots” or “liver spots” appear and grow, along with wrinkling and sagging. Due to changes in the number of sweat glands and shrinking capillary beds in the skin, elderly people are less able to tolerate the cold and cannot regulate heat. Older skin has a diminished ability to activate vitamin D necessary for skeletal health.