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14 Cards in this Set

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  • 3rd side (hint)
What is a biofilm?
communities of microorganisms attached to a solid surface; the surface can either be nonliving or living tissue.
Co-biofilms of ______and _____are associated with serious lung infections in patients with ______
Pseudomonas and Burkholderia are associated with serious lung infections in patients with cystic fibrosis
Associated with serious lung infections in patients with cystic fibrosis.
Co-biofilms of Pseudomonas and Burkholderia
The sessile phenotype results from attachment and usually develops into a ________biofilm that has unique characteristics, making it similar in many ways to__________
multispecies biofilm that has unique characteristics, making it similar in many ways to hydrated polymers
The _________ results from attachment and usually develops into a multispecies biofilm that has unique characteristics, making it similar in many ways to hydrated polymers
sessile phenotype
________,______analogous to bacterial spores,are present in all biofilms and bacterial populations.
Persister cells.
Essential metabolically inert microorganisms.
Persister cells.
Essential metabolically inert microorganisms.
are present in all biofilms and bacterial populations.
Are hypothesized to have disabled programmed cell death, or apoptosis
Persister cells
These cells have the greatest potential for maintenance of the gene pool and resistance to environmental stress, including antimicrobial agents
Persister cells
How do biofilm protect bacteria.
(3ways)
-Phagocytic cells are generally unable to penetrate the biofilm
-PMNs will degranulate and cause damage to nearby host tissue
-may hide microbial agents, preventing an immune response on blocking interaction with antibody
-Barrier
-PMN's
-Immune
The ________of the biofilm is where the bacteria are attached to the substratum and represents the earliest part of the biofilm.
innermost layer
where the bacteria are attached to the substratum and represents the earliest part of the biofilm
innermost layer
Biofilm level of least metabolic activity question:
Where are most persister cells are located?
Located where the bacteria are attached to the substratum
where the bacteria are attached to the substratum is where the________ cells are located.
most persister cells are located?