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19 Cards in this Set
- Front
- Back
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______ immunity 1st line of defense |
Innate Intact skin Mucus membranes Normal microbiota |
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Second line of defense examples ____ immunity |
Innate immunity Phagocytes, such as neutrophils eosinophils, Dendritic Cells, and macrophages |
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3rd line of defense ______ immunity |
Specialized lymphocytes: T and B cells Antibodies |
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Phagocytes ingests ______ in process called ______ |
Microbes Phagocytosis |
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Chemotaxis - phagocytes use ______ to travel along chemokine gradient to site of infection |
Pseudopods |
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Phagocytes bind to ______ on microbes |
PAMPS |
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Example of PAMPS |
LPS layer of Gram Negative Cells, Peptidoglycan or Teichoic acids from gram positive cells |
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Innate reaction to nonspecific stimuli such as toxins, pathogens, or mechanical damage |
Inflammation |
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Goal of inflammation |
Localize infection to one area! Remove microbe |
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Inflammation process 1.Signal _____ to site 2.______ : causes inflammation symptoms migration and _____ 3. _____migration and _____ 4. ______ repair
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Phagocytes Vasodilation Phagocyte and phagocytosis Tissue |
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Fever response is a ____ response to microbe infection |
Systemic |
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Fever response Symptoms: Pros: Cons: |
Body temperature rising/sweat (crises stage High temp inhibits microbes Rapid Heart rate, dehydration |
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Cytokines are any cell ______ molecule that aid in cell to cell communication in _____ _____ |
Signalling Immune responses |
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Iron binding proteins like ______ work to outcompete bacteria siderophores |
Transferrin |
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Interferon cytokine induce body cells to make _____ ______ proteins that block ______ replication |
Anti viral Viral |
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_____ and _____ bind to mast cells and triggers histamine release |
C3a and C5a |
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Cytolysis is triggered by ___-_____ and trigger osmotic lysis of cell |
C5b-C9 |
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3 Pathways that activate the C3 Cascade |
Classic pathway Alternative pathways Lectin Pathway |
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Classical pathway - activated by _____ Alternative Pathway - activated by ____ Lectin Pathway - activated by _____ |
Antibodies Complement proteins binding to PAMP Lectin Proteins |
