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14 Cards in this Set

  • Front
  • Back

Factors against infections

1.no receptor


2.antimicrobial factors


3.indigenous microbiota


4.nutrition of individual


5.immunity


6.phagocytes wbc

Incubation period

Time from arrival of pathogen and onset of symptoms

Prodromal period

Patieny feels out of sorts but no actual symptoms coming down with it

Convalescent period

Although the patient may be recovered permanent damage may be present. Ie defness after ear infection

Signs of disease

Objective. Lab results

Steps in pathogenesis of infectious disease

1.entry


2.attachment


3.multiplication


4.invasion


5.evasion of host defenses


6.damage to host tissue

Virulence factor

Phenotypic characteristic that enables microbes to be virulent like flagella capsules

Adhesion and ligand

The molecules on a pathogen that bind to a specific receptor

Necrotizing enzymes

Destroy tissues S.pyogenes, clostridium

Kinases

Dissolve clots s. Aurus , staph, strep

Hyslundronidase

Spreading factor dissolve collagen


Clostridium perfringes

Endotoxins

Integral parts on gram neg cell walls

Antigenic variation

When pathogens change theur surface receptors making them harder to kill

Molecular mimicry

Pathogen covers self with host proteins