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13 Cards in this Set
- Front
- Back
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Antibacterial drug mode of action |
Cell wall synthesis inhibitors Inhibit NAG n NAM or linking to firm chains |
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Nucleic acid syntbesis inhibitors |
Nucleotide synthesis Enzymes involved in replication m transcription |
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Protein inhibitors |
Translation Block peptide bond from forming |
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Cellmembrane alterations |
Most bind to diff sterols that are part of membrane ir lipids if dustinct enough |
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Metabolic enzyme inhibitors |
All Currently focus on folic acid synthesis Great selective toxic Target only damaged micro is not damaged host |
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Antifungal drug modes of action 1.Macrolide polyenes |
Binds to fungal membranes Others mimic lipids structure of phospholipids Topical and systemic uses |
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Antifungal Azoles |
Interfere with sterols synthesis In use for many years so it can be administered systemically most topical |
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Antifungal Echinocandins |
Inhibit fungal cell wall synthesis |
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Flucytosine |
Nucleotide analog of cytosine Main benefit is rapid uptake |
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Gruseofulvin-dermatophytes |
Inhibits microtubule formation Toxic low does for long time |
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Antiviral |
Inhabitation of viral entry Habitation of viral assembly and release |
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Antihelminthic drugs Antimetabolites |
Benzimidizole-stop microtubule formation Ivermectin |
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Antiprotozoan drugs |
1. Antimetabolites, many affect Trypanosomes 2. Dna synthesis inhibitors 3. Antimalarial drugs- mode of action unknown |
