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5 Cards in this Set

  • Front
  • Back

Which of the following coenzymes is unique to -keto acid dehydrogenase complexes?


A. NAD


B. FAD


C. GDP


D. H2O


E. Lipoic acid

E. Lipoic acid

A patient diagnosed with thiamine deficiency exhibited fatigue and muscle cramps. The muscle cramps have been related to an accumulation of metabolic acids. Which of the following metabolic acids is most likely to accumulate in a thiamine deficiency?


A. Isocitric acid


B. Pyruvic acid


C. Succinic acid


D. Malic acid


E. Oxaloacetic acid

B. Pyruvic acid

Succinate dehydrogenase differs from all other enzymes in the TCA cycle in that it is the only enzyme that displays which of the following characteristics?


A. It is embedded in the inner mitochondrial membrane.


B. It is inhibited by NADH.


C. It contains bound FAD.


D. It contains Fe–S centers.


E. It is regulated by a kinase.

A. It is embedded in the inner mitochondrial membrane.

During exercise, stimulation of the TCA cycle results principally from which of the following? A. Allosteric activation of isocitrate dehydrogenase by increased NADH


B. Allosteric activation of fumarase by increased ADP


C. A rapid decrease in the concentration of four-carbon intermediates


D. Product inhibition of citrate synthase


E. Stimulation of the flux through a number of enzymes by a decreased NADH/NAD ratio

E. Stimulation of the flux through a number of enzymes by a decreased NADH/NAD ratio

Coenzyme A is synthesized from which of the following vitamins?


A. Niacin


B. Riboflavin


C. Vitamin A


D. Pantothenate


E. Vitamin C

D. Pantothenate