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8 Cards in this Set

  • Front
  • Back
What is the most common generalized lympadenopathy in individuals >60?
CLL
What is the most common overall leukemia?
CLL
What is the pathogenesis of Chronic Lympocytic Leukemia?
Neoplastic disorder of virgin B-cells( b-cells that can't differentiate
What are the clinical findings of CLL?
Lymphadenopathy
Metastatic sites similar to AML
Increased incidence of immune hemolytic anemia: Warm (IgG) and Cold (IgM)
What are the Lab Findings of CLL
WBC: 15,000-200,000/uL
---Lympho less than 10%
----Neutropenia
----Smudge cells ( Fragile leukocytes)
What type of anemia is found in CLL?
Normocytic ~50% and thrombocytopenia ~40%
What are the bone marrow findings for CLL?
Bone marrow is usually replaced with neoplasitc B-cells
What is commonly found with the immunoglobins?
hypogammaglobulienemia