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12 Cards in this Set

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Benzodiazepines

a chemical category of drugs most frequently prescribed as anxiolytic (anxiety relieving) drugs and less frequntely as sedative drugs

hypnotics

drugs that when given at low to moderate dosages calm or soothe the CNS without inducing sleep but when given at high dosages cause sleep

long acting hypnotic benzodiazepines

fluerazepan or trade name (Dalmane)


estazelam (prosom)


intermediate hypnotic benzodiazepines

lorazepam or trade name (ativan)


short- acting hypnotic benzodiazepines

eszopiclone or trade name (lunesta)


zolpiden (ambien)


Mechanism of action

depress activity in CNS


affect hypothalamus, thalamic, and limbic systems of brian


drug affects

calming effect on CNS by inhibiting GABA (gamma- aminobutyric acid) receptors

indications of benzodiazepines

sedation


sleep induction


sleep relaxation


some treatment of alcohol withdrawal


treatment of acute seizure disorders


reilef of agitation or anxiety

adverse effects

mild and infrequent but includes:


headache


drowsiness


dizziness


vertigo


lethargy


toxicity and overdose

somnolence


confusion


coma


diminished reflexes


antidote for benzodiazepines

flumazenil

interactions to benzodiazepines

other CNS depressants (alcohol and opioids)


herbal drugs (kava and valerian)


grapefruit juice