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2 Cards in this Set
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Sulfonamides and Trimethoprim
[TYPE] [Action] [AV] |
[Broad spectrum antibiotics]
Suppress bacterial growth by inhibiting folic acid Urinary tract infections Adverse effects: Hypersensitivity reactions-Stevens-Johnson syndrome Hematologic effects Kernicterus-not for under 2 yo Crystalluria-can occur in high renal concentrations, **hydration important** |
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Trimethoprim-Sulfamethoxazole
[TMP-SMZ] [USES] [AV] |
The TMP-SMZ combo inhibits sequential steps in bacterial folic acid synthesis, making it much more powerful than TMP or SMZ alone.
Uses: Uncomplicated urinary tract infection Pneumocystis carinii S. Maltophilia – GI infections Adverse effects: Gastrointestinal Rash – Crystalluria |
