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30 Cards in this Set

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Cross-sensitivity

Meds that share common actions may also share common adverse effect

Anaphylactic

Severe, total body life threatening adverse reaction.


May result from administration of any drug.

Classification of med

Helpful for implementation of appropriate actions before administrating med. This can prevent overdose or adverse reactions

FDA pregnancy categories

Cat A - no risk documented


Cat b- animal studies have no risk, on humans it has inadequate risk. Also flipped around.


Cat C- animal studies have adverse effects, no adequate studies in human, or no adequate studies in both.


Cat D- human fetal risk, benefits may out wight potential risk


Cat X- abnormalities documented


Key concept

A person may be allergic to any med at any time, always watch for signs, also ask if any other med are being taken, mixed together can have serious sideffect

Food and meds

Some meds interact negatively with certain foods. Some meds should be taken with food, while others with empty stomach

Drug and drug interactions

Can have possible interaction that lead to decreased effects, or overdose of the drug.

Meds not to be taken with grapefruit juice

Anti infective agent

Medication used to treat an infection

Antibiotic

Type of anti infective agent, is a chemical compound use to treat bacterial infections

Antibiotic classes

Broad spectrum- effective against many organisms.


Narrow spectrum- effective against only a few MO.


Bacteriostatic

Antibiotics that retard the growth of bacteria.

Bactericidal

Kill bacteria

Speed of action of med

Controlled release- slowly released over time


Delayed release- begins after period of time.


Extended release- release over long period of time


Immediate release- immediately


Sustained release- release over period of time


Depot, decanoate- release for 2-3 weeks


Transdermal - release for 12hr to 30 days



Key comcept

Many antibiotics reduce the bacteria strenght, our body then take over to actually kill pathogen

Antibiotic effectiveness

Must be soluble in water, and diffuse readily into body tissue.


Should not cause allergic, or affect normal flora, or antagonist to other antibiotics

Antibiotic resistant organism

When antibiotics are used indiscriminately, or administer improperly. Certain pathogen mutate and form a resistance

Selecting appropriate antibiotic

Order a C&S test, to determine the MO, then we determine what antibiotic it's most sensitive to.

Key concept

To ensure accurate results, antibiotic therapy should not start until after C&S is obtained

Most common antibiotics

Penicillin, cephalosporins, tetracycline, aminoglycoside, macrolides, & sulfonamides

Penicillin

Kills bacteria, bactericidal. Available in liquid, tablets, parenteral forms. Safest is oral route.

Penicillin side effects

Only to 5% of North America. Mild effects are nausea, sore mouth, diarrea. More severe are hives, fever, rash, dyspnea

Cephalosporins

Like PCN, devoted from mold. 10% of people allergic to PCN also allergic to cephalosporins. Divided into 3 groups; 1st,2nd,3rd generation and are based on range of medications specificity. Used frequently for mixed infections.

Nursing alert

If patient drinks alcohol while taking cephalosporins, severe nausea and vomiting are likely

Tetracycline TCN

A broad spectrum antibiotics that's effective against wide variety of organisms. Often used for patient allergic to PCN. To promote absorption, should be taken on empty stomach.


Side effects can include photosensitivity, nausea, vomiting, diarrhea

Aminiglycoside

Potent bactericidal antibiotic. Active against aerobic gram negative organisms, particularly those causing UTI and life threatening septicemias. Can cause ototoxicity and nephrontoxicity

Ototoxicity

Cause by damage to eight cranial nerve, causing hearing loss, diziness, and tinnitus

Nephrontoxicity

Kidney damage, manifested by blood and protein in the urine

Macrolide antibiotic

Are narrow spectrum bactrriostatic agents. Effective against most MO that are sensitive to PCN and are used to treat respiratory tract infections in clients allergic to PCN.

Sulfonamide

Are bacteriostatic agents Used for antimicrobial agents. They are being replace by better agents.