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11 Cards in this Set
- Front
- Back
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What is the adaptive immune system mediated by?
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B and T cells
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Would an adaptive immune system receptor for the 1976 Flue respond to antigens for the Flu of 1975 or 1977
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no, adaptive immune system receptors are highly specific
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What are the 2 types of T-cells and what is their job?
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cytotoxic T-cells: kill altered self cells (like NK cells in innate immune system)
T-helper cells: secrete cytokines (show other cells what to do; similar to phagocytes in innate immune system) |
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What is the function of B-cells?
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make antibodies (Ab), also known as immunoglobulins (Ig)
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What are the Ab isotypes?
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IgM, IgA, IgD, IgG, IgE
(MADGE) |
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Which immunoglobulin is important for allergic responses?
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IgE
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What are the 5 functions of antibodies (Abs)
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neutralize, activate complement, opsonize pathogen, activate mast cells to degranulate, mark pathogen for killing by NK cells
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When do B and T cells encounter the antigen for the first time?
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primary response
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What do B and T cells do in response to the antigen during the primary response?
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clonal expansion: divide and form many clones of themselves to fight pathogen
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What is the source of defense in the memory (secondary) response?
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clones of B and T cells that lived on as memory cells
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What happens if the same pathogen is encountered a second time?
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memory cells are easily activated (respond and kill pathogen before it causes disease)
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