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21 Cards in this Set
- Front
- Back
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3 molecules for communication
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Receptors
Ligands Secondary Messengers |
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Receptors
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on surface of cells and partically embedded in membrane
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Ligands
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binds to receptors
ex. hormones directly enter cell after it is received. |
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Secondary Messengers
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Signal inside cell and amplify message
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4 types of drugs
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antagonist
agonist drugs that decrease [messengers] drugs that inc [messengers] |
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antagonist drug
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blocks receptors
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agonist drug
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competes with messengers for receptor cite
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vessicles
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presynaptic bulbs that store and release neurotransmitters
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ednocrine glands
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secrete hormones
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main diff b/t neurotransmitters and hormones
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the distance they travel
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can be neurotransmitters or hormones
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ligands
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5 classes of chemical messengers
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cholinergic
amino acid adrenic messengers peptergic steroid |
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cholinergic ligands
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1. Ca2+ stimulates release of acetylchoine
2. acetylcholine travels synapse and bonds to receptor 3. binding to receptor causes conformation change and Na+ enters --> electricity! |
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two types of amino acid ligands
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excitory neurotransmitters
inhibitory neurotransmitters |
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adrenic messengers
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absorbed by cell, signal amplified through cascade effect
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examples of adrenic messengers
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dopamine
histamine |
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Peptergic messengers
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peptides that are messengers
involved in metabolism |
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example of peptergic messenger
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insulin
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insulin
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allows glucose to enter cell by activating cyclic GMP to allow glucose to enter
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steroid messngers
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can enter cell through diffusion; no receptors
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Breast cancer
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too much estradiol
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