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15 Cards in this Set
- Front
- Back
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Acylation
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Addition of an acyl group, usually replacinga H atom. Acylation of an amine gives an amide.
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Acylation-reduction
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a method for synthesizing amines by acylating ammonia or an amine, then reducing the amide.
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Amine
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a derivative of ammonia with one or more alkyl or aryl groups bonded to the nitrogen atom.
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Amine oxide
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an amine with a fourth bond to an O atom. In the amine oxide, the N atom bears a pos charge, and the O atom bears a neg charge.
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Ammonium salt (amine salt)
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a derivative of an amine with a postively charged N atom having 4 bonds. An amine is protonated by an acid to give an ammonium salt.
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Azide
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a compound having the azido group, -N3.
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Cope elimination
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a variation of the Hofmann elimantion, where a tertiary amine oxice elimantes to an alkene with a hydroxlyamine serving as the leaving group.
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diazo coupling
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the use of a diazonium salt as an electrophile in electrophilic aromatic substitution.
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diazotizationn of an amine
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the reaction of a primary amine with nitrous acid to form a diazonium salt.
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exhaustive alkylation
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treatment of an amine with an excess of an alkylating agent (often methyl iodide) to form the quaternary ammonium salt.
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Gabriel Amine Synthesis
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Synthesis of primary amines by alkylation of the potassium salt of phtalimide, foolowed by displacement of the amine by hydrazine.
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Hofmann elimination
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elimination of a quatenary ammonium hydroxide with an amine as the leaving group. the Hofmann elimination usually gives the LEAST highly substitued alkene.
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hydroxlyamine
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the compound H2NOH,or generically, an amine in which a hydroxyl group is one of the 3 substiutents bonded to N.
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phase-transfer catalyst
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a compound (sucha s a quaternary ammonium halide) that is soluble in booth water and organic solvents and that helps reagents move between organic and aqueous phases.
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reductive amination
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the reduction of an imine or oxime derivative of a ketone or aldehyde.
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