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25 Cards in this Set

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What is the usual age of onset for schizophrenia?
Between late teens and early thirties
Are men or women more likely to develop late onset schizophrenia?
Women -- generally over the age of 45
What are the biologic theories of the etiology of schizophrenia
-Inherit predisposition
-Brain anatomy changes that involve decreased blood flow to the brain, thinner cortex, decreased brain matter and widened sulci
-Positive symptoms may be caused by dopamine hyperactivity in the mesolimbic tract
What are the psychological theories of the etiology of schizophrenia?
Obsolete
What are the social theories of the etiology of schizophrenia?
Family emotional tone may aggravate the condition, but won't cause it
What are comorbidities of schizophrenia?
-Increased risk of medical problems including cardiovascular disease, obesity, diabetes
-Depression and suicide
-Substance abuse
-Cigarette smoking
What is the DSM Diagnostic Criteria for Schizophrenia?
During a one-month period at least 2 of 5 of the following are present:
-Delusions
-Hallucinations
-Disorganized speech
-Grossly disorganized or catatonic behavior
-Negative symptoms (alogia, anhedonia, flat affect, avolition, apathy)
Note: only one symptom need be present if the delusion or hallucination involves a running commentary
What are examples of positive symptoms or schizophrenia?
Hallucinations
Delusions
Thought Disorder
What are 7 types of delusions?
1. Persecutory
2. Reference
3. Grandiose
4. Nihilistic
5. Somatic
6. Religious
7. Substitution (belief that an individual is someone else)
What are 5 examples of disorganized speech?
1. Loose associations
2. Word salad
3. Clang Associations
4. Echolalia
5. Perseveration
What are 5 examples of disorganized or catatonic behavior?
1. Catatonic excitement (extreme motor agitation)
2. Waxy flexibilty (maintains rigid position, but moveable)
3. Catatonic posturing
4. Catatonic stupor (seemingly unaware of surroundings
5. Echopraxia
What are 5 examples of negative symptoms?
1. Affective blunting
2. Anhedonia
3. Avolition (inability to pursue and persist in goal-directed behavior or activities
4. Alogia (also called poverty of speech)
5. Apathy
What are the phases in the course of schizophrenia?
Acute phase
Stabilization phase
Maintenance Phase
What are factors of recurrent acute exacerbations of psychosis?
-Relapse (irreversible) prevention vs. medication side effects (reversible)
-Residual dysfunction (baseline increases over time even after relapse)
-Pattern of illness: the course of illness over the first three years is indicative for the lifetime
-Vulnerability to stress
What are 5 types of schizophrenia?
1. Paranoid
2. Disorganized
3. Catatonic
4. Undifferentiated
5. Residual
What is a sign of catatonic schizophrenia?
Echolalia
What is residual schizophrenia?
One documented episode but no prominent positive symptoms
What is Schizophreniform Disorder?
-Criteria A, D, and E for schizophrenia
-Episode lasts at least 1 month but less than 6 month
-Usually no impairment in social or occupational functioning
-May be prodromal to schizophrenia
-Has a 1/3 recovery rate
What is Schizoaffective Disorder?
Uninterrupted period of illness during which there is a major depressive, manic, or mixed episode concurrent with two Criterion A symptoms for schizophrenia.
-Risk for suicide
-Less common than schizophrenia
-More common in women, but develped later
What is Delusional Disorder?
Stable, well systemized and logical, nonbizarre delusions that occur in the absence of other psychiatric disorders for at least 1 month. Patients function well in areas not related to delusion. It's uncommon.
When is the typical onset for Delusional Disorder?
Middle and late adulthood
What are 6 types of delusional disorder?
1. Erotomanic
2. Jealous
3. Unspecified
4. Grandiose
5. Somatic
6. Persecutory
What is a brief psychotic disorder?
One of more Criterion A symptoms for schizophrenia present for at least 1 day but less than 1 month. Patients return to the prior level of functioning. Episode may be due to stressful event. This disorder is rare and seldom seen.
What are some pharmacologic interventions for schizophrenia?
Serotonin-dopamine antagonists: block dopamine and serotonin receptors. They are newer and have less extrapyramidal side effects.
What are examples of pharmacologic interventions that are effective for negative symptoms?
Risperidone
Seroquel
Clozapine (2nd line of defense)