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33 Cards in this Set

  • Front
  • Back
% of obese americans
25-50%
Definition of obesity
>20% over ideal weight
BMI >30
BMI 25-29 = overweight
BMI formula
BMI = lb x ((705/70)/70)
How is overweight defined in children?
at or above 95th percentile (sex specific)
explain how obesity varies among populations
Varies by ethnic group in women, but not in men.
Childhood obesity is highest in what 2 ethnic groups?
Mexican American
African American
Ages 12-19yo
What is Pickwickian Syndrome
body weight more than 2x normal, respiratory, CV, and sleep problems
Is obesity an eating disorder?
No.
2 genes implicated in obesity
Leptin receptor (LEPR)
Melanocortin 4 receptor (MC4R)
Most weight lost with diet is regained in...
5 years
surgery in which food is rerouted past part of stomach and SI
gastric bypass
surgery in which size of stomach is reduced
bariatric surgery
Class of drugs once used for weight loss, now rare.
Amphetamines
Amphetamine like agent still rx'd for obesity
phentermine (Ionamin)
fenfluramine and denfenfluramine were taken off market because
they caused heart valve abnormalities
How does Orlistat (Xenical) work
pancreatic lipase inhibitor. Limits breakdown of dietary fats, dec-ing absorption 33%
How does sibutramine (Meridia) work
block monoamine reuptake, increasing satiety
Diet that may produce more weight loss of BETTER heart risk factors
Atkins
Purging can lead to what complications
malnutrition
electrolyte disturbances
CV problems (arrythmias)
what is melanosis coli
blackened area of mucosa, sign of laxative abuse
What is hypergymnasia
excessive sports activity, mostly gymnastics and ballet
Differential of eating disorders
occult malignancy
regional enteritis
chronic infection
MDD
Kleine Levin syndrome
borderline personality
life threatening eating disorder
anorexia nervosa (18%)
Common metabolic abnormality associated with arrythmias
hypokalemia
Diagnostic criteria for anorexia
body weight <85% or normal
BMI <17.5
fails to gain weight
Strong fear of gaining weight
Disturbed body image
3 consecutive missed periods
2 stages of anorexia tx
1. restore body weight
2. prevent relapse
Pt should be admitted to hospital when?
body weight is 20% or more below normal
Rx's for anorexia
amitriptyline (Elavil, antidep.)
fluoxetine (Prozac, SSRI)
Cyproheptadine (Periactin, appetite stimulant)
Most effective form of psychotherapy for anorexia
family therapy
Criteria for bulemia nervosa
recurrent episodes of binge eating coupled with feeling out of control over the binge eating during the episode. 2x/week for at least 3 mos.

Usually some type of compensatory mechanism (laxatives, vomiting, etc)
Consequences of repeat vomiting
Parotid gland swelling/infection
tooth enamel erosion
dental caries
What if a patient has features of anorexia, but purges
Anorexia, binge-eating/purging type
Bulemia tx
cognative/behavioral therapy
Antidepressants (HCA's, MAOI's, SSRIs (fluoxetine (Prozac))).

Combo drugs +therapy is more effective than alone.