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67 Cards in this Set

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adrenal gland
a gland on the upper surface of the kidney. The outer region (cortex) secretes steroid hormones; the inner region (medulla) secreted epinephrine (adrenaline) and norepinephrine (noradrenaline) (root adren/o)
endocrine
pertaining to a ductless gland that secretes directly into the blood
hormone
a secretion of an endocrine gland. A substance that travels in the blood and has a regulatory effect on tissues, organs, or glands
hypophysis
the pituitary gland (root hypophys); named from hypo meaning "below" and physis meaning "growing" because the gland grows below the hypothalamus
hypothalamus
a portion of the brain that controls the pituitary gland and is active in maintaining homeostasis
pancreatic islets
Clusters of endocrine cells in the pancreas that secrete hormones that regulate sugar metabolism; also called islets of Langerhans or islet cells (root insul/o, meaning "island"
parathyroid glands
small glands on the back of the thyroid that act to increase blood calcium levels; there are usually four to six parathyr/o, parathyroid/o); the name literally means "near the thyroid"
pituitary gland
a small endocrine gland at the base of the brain. The anterior lobe secreted growth hormone and hormones that stimulate other glands; the posterior lobe releases ADH and oxytocin manufactured in the hypothalamus
prostaglandins
a group of hormones produced throughout throughout the body that have a variety of effects, including stimulation of uterine contractions and regulation of blood pressure, blood clotting, and inflammation
receptor
a site on the cell membrane to which a substance, such as a hormone, attaches
steroid hormone
a hormone made from lipids including the sex hormones and the hormones of the adrenal cortex
target tissue
the specific tissue on which a hormone acts; may also be referred to as the target organ
thyroid gland
an endocrine gland on either side of the larynx and upper trachea. It secretes hormones that affect metabolism and growth and a hormone that regulates calcium balance (root thyr/o, thyroid/o)
endocrin/o
endocrine glands or system
pituitar
pituitary gland, hypophysis
hypophys
pituitary gland, hypophysis
thyr/o, thyroid/o
thyroid gland
parathyr/o, paratyroid/o
parathyroid gland
adren/o, adrenal/o
adrenal gland, epinephrine
adrenocortic/o
adrenal cortex
insul/o
pancreatic islets
acromegaly
overgrowth of bone and soft tissue, especially in the hands, feet, and face, caused by an excess of growth hormone in an adult. The name comes from acro meaning "extremity" and megal/o meaning "enlargement"
Addison disease
A disease resulting from the deficiency of adrenocortical hormones. It is marked by darkening of the skin, weakness, and alternations in salt and water balance
adenoma
a neoplasm of a gland
congenital
a condition caused by congenital lack of thyroid secretion and marked by arrested physical and mental development; formerly called cretinism
Cushing disease
Overactivity of the adrenal cortex resulting from excess production of ACTH by the pituitary
Cushing syndrome
A condition resulting from an excess of hormones from the adrenal cortex. It is associated with obesity, weakness, hyperglycemia, hypertension, and hirsutism (excess hair growth)
diabetes insipidus
A disorder caused by insufficient release of ADH from the posterior pituitary. It results in excessive thirst and production of large amounts of very dilute urine. The word insipidus means "tasteless", referring to the dilution of urine
diabetes mellitus
A disorder of glucose metabolism caused by deficiency of insulin production or failure of the tissues to respond to insulin. Type 1 is juvenile-onset or insulin-dependent diabetes mellitus (IDDM); type 2 is adult-onset or non-insulin-dependent diabetes mellitus (NIDDM). The word mellitus comes from the Latin root for honey, referring to the sugar content of the urine
exophthalmos
protrusion of the eyeballs as seen in Graves disease
gigantism
overgrowth caused by an excess of growth hormone from the pituitary during childhood; also called giantism
glycosuria
excess sugar in the urine
goiter
enlargement of the thyroid gland. May be toxic or nontoxic. Simple (nontoxic) goiter is caused by iodine deficiency
Graves disease
An autoimmune disease resulting in hyperthyroidism. A prominent symptom is exophthalmos (protrusion of the eyeballs). Also called exophthalmic goiter
hyperglycemia
excess glucose in the blood
hypoglycemia
abnormally low level of glucose in the blood
insulin shock
a condition resulting from an overdose of insulin, causing hypoglycemia
ketoacidosis
acidosis (increased acidity of body fluids) caused by an excess of ketone bodies, as in diabetes mellitus; diabetic acidosis
metabolic syndrome
a state of hyperglycemia caused by cellular resistance to insulin; as seen in type 2 diabetes, in association with other metabolic disorders; syndrome X or insulin resistance syndrome
myxedema
a condition caused by hypothyroidism in an adult. There is dry, waxy smelling most notable in the face
panhypopituitarism
underactivity of the entire pituitary gland
panhypopituitarism
underactivity of the entire pituitary gland
tetany
irritability and spasm of muscles; may be caused by low blood calcium and other factors
pineal gland
a small gland in the brain. Its function in humans is not clear, but it seems to regulate behavior and sexual development in response to environment light
sella turcica
a saddle-shaped depression in the sphenoid bone that contained the pituitary gland (literally means "Turkish saddle")
sphenoid bone
a bone at the base of the skull that houses the pituitary gland
adrogenital syndrome
condition caused by overproduction of androgens from the adrenal cortex, resulting in masculinization; may be congenital or acquired, usually as a result of an adrenal tumor
Conn syndrome
Hyperaldosteronism caused by adrenal tumor
craniopharyngioma
a tumor of the pituitary gland
Hashimoto disease
a chronic thyroiditis of autoimmune origin
ketosis
accumulation of ketone bodies, such as avetone, in the body. Usually results from deficiency or faulty metabolism of carbohydrates, as in the case of diabetes mellitus and starvation
multiple endocrine neoplasia (MEN)
a hereditary disorder causes tumors in several endocrine glands; classified according to the combination of glands involved
pheochromocytoma
a usually benign tumor of the sdrenal medulla or other structures containing chromaffin cells (cells that stain with chromium salts). The tumor causes increase production of epinephrine and norpeinephrine
pituitary apoplexy
sudden massive hemorrhage and degeneration of the pituitary gland associated with a pituitary tumor. Common symptoms unclude sever headache, visual problems, and loss of consciousness.
Simmonds disease
Hypofunction of the anterior pituitary (panhypopituitarism), usually because of an infarction; pituitary cahcexia
thyroid storm
a sudden onset of the symptoms of thyrotoxicosis occurring in patients with hyperthyroidism who are untreated or poorly treated. May be brought on by illness or trauma. Also called thyroid crisis.
thyrotoxicosis
condition resulting from overactivity of the thyroid gland. Symptoms include anxiety, irritability, weight loss, and sweating. The main example of thyrotoxicosis is Graves disease
von Reckilnghausen disease
degeneration of bone caused by excess production of hormone from the parathyroid glands. Also called Recklinghausen disease of born
fasting plasma
measurement of glucose in the blood after a fast of atlease 8 hours. A reading equal to or less than 126mg/dL indicates diabetes. Also called fasting blood glucose (FBG) or fasting blood sugar (FBS)
free thyroxine index (FTI, T7)
claculation based on the amount of T4 present and T3 uptaked that is used to diagnose thyroid dysfunction
glycosylated hemoglobin test
a test that measures the bidning of glucose to hemoglobin during the lifespan of the red blood cell. It reflects the average blood glucose level over 2 to 3 months and is useful in evaluating long-term therapy for diabetes mellitus. Also called glycohemoglobin test
oral glucose tolerance test (OGTT)
measurement of glucose levels in the blood plasma after administration of a challenge dose of glucose to a fasting patient. Used to measure patient's ability to metabolize glucose. A value equal to or less than 200mg/dL in the 2-hour sample indicates diabetes
radioactive iodine uptake test (RAIU)
a test that measures thyroid uptake of radioactive iodine as an evaluation of thyroid function
radioimmunoassay (RIA)
a method of measuring very small amounts of a substance, especially hormones, in blood plasma using radioactively labeled hormones and specific antibodies
thyroid scan
visualization of the thyroid gland after administration of radioactive iodine
thyroxine-binding globulin (TBG) test
test that measures the main protein that binds T4 in the blood
transsphenoidal adenomectomy
removal of a pituitary tumor through the sphenoid sinus (space in the sphenoid bone)