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10 Cards in this Set
- Front
- Back
- 3rd side (hint)
Location of a receptors:
Responds to which hormone? 524 |
Binding of norepinephrine on A receptors results in:
Higher affinity for norepinephrine than epinephrine |
Vasoconstriction
Blood diverted from gi tract to skeletal muscles, liver, and heart |
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B2 receptors locations
Binds to what hormones? 524 |
Vascular smooth muscle of the heart, liver, and skeletal muscle arterioles
Binding of epinephrine results in: |
Vasodilation
Increase blood to.heart, liver, skeletal muscles Remember, no innervation, only responds to circulating epinephrine |
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Continuous capillaries
Found in what parts of the body? |
Most common capillary, found in muscle, connective tissue, and neural tissue.
Important in blood brain barrier. Role of tight junctions? |
Protects neural tissue from toxins in bloodstream
Junctions are not large enough for blood cells and proteins to through. |
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Fenestrated capillaries
Found in which parts of the body? |
Kidneys, intestine, absorptive transporting epithelia
They have large pores to allow high volumes of fluid to pass rapidly. most dissolved solutes diffuse freely |
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Sinusoids
Found where? |
Locations where blood cells and plasma proteins need to cross the endothelium to hey into the blood.
1. Bone marrrow 2. Liver- lack of basal lamina allows more free exchange 3. Spleen Sinusoids are not typical, they are 5 times wider than a capillary. They have fenestrations and may have gaps in between the cells |
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Transcytosis
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How larger molecules molecules (and select proteins) are transported across endothelium
Endothelia fitted with caveolae and nonciated pits to form vesicles |
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Bulk flow
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Mass movement of fluid regulated by hydrostatic and osmotic pressure gradients.
Osmotic pressure determined by solute concentration between plasma and interstitial fluid, mainly by proteins in the plasma, mostly absent in interstitial fluid 1. Absorption- bulk flow into capillary 2. Filtration- bulk flow out of capillary. Caused by hydrostatic pressure that forces fluid out of capillary through leaky junctions |
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Colloid osmotic pressure (bulk flow)
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Osmotic pressure created by proteins.
Solutes do not contriibute because they can freely cross the endothelium. Favors movement of water from interstitial fluid to the plasma Is constant along length of capillary |
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Capillary hydrostatic pressure
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Decreases along length of capillary because loss of energy to friction
Pressure of capillary at Arterial end: 33 mmhg Venous end: 15 mmhg Interstitial fluid: 0 Means water movement goes out of the capillaries |
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Filtration
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I
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