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17 Cards in this Set

  • Front
  • Back

anticodon

A nucleotide triplet at one end of a tRNA molecule that base-pairs with a particular complementary codon on an mRNA molecule.

codon

A three-nucleotide sequence of DNA or mRNA that specifies a particular amino acid or termination signal; the basic unit of the genetic code.

exon

A sequence within a primary transcript that remains in the RNA after RNA processing; also refers to the region of DNA from which this sequence was transcribed.

intron

A noncoding, intervening sequence within a primary transcript during RNA processing; also refers to the region of DNA from which this sequence was transcribed.

reading frame

On an mRNA, the triplet grouping of ribonucleotides used by the translation machinery during polypeptide synthesis.

ribosome

A complex of rRNA and protein molecules that functions as a site of protein synthesis in the cytoplasm; consists of a large subunit and a small subunit. In eukaryotic cells, each subunit is assembled in the nucleolus.

RNA polymerase

An enzyme that links ribonucleotides into a growing RNA chain during transcription, based on complementary binding to nucleotides on a DNA template strand.

RNA processing

Modification of RNA primary transcripts, including splicing out of introns, joining together of exons, and alteration of the 5' and 3' ends.

template strand

The DNA strand that provides the pattern, or template, for ordering, by complementary base pairing, the sequence of nucleotides in an RNA transcript.

transcription

The synthesis of RNA using a DNA template.

transcription unit

A region of DNA that is transcribed into an RNA molecule.

translation

The synthesis of a polypeptide using the genetic information encoded in an mRNA molecule. There is a change of "language" from nucleotides in amino acids.

triplet code

A genetic information system in which a series of three-nucleotide-long words specifies a sequence of amino acids for a polypeptide chain.

wobble

Flexibility in the base-pairing rules in which the nucleotide at the 5' end of a tRNA anticodon can form hydrogen bonds with more than one kind of base in the third position (3' end) of a codon.

tRNA

An RNA molecule that functions as a translator between nucleic acid and protein languages by picking up a specific amino acid and carrying it to the ribsome, where the tRNA recognizes the appropriate codon in the mRNA.

rRNA

RNA molecules that, together with proteins, make up ribosomes; the most abundant type of RNA.

mRNA

A type of RNA, synthesized using a DNA template, that attaches to ribosomes in the cytoplasm and specifies the primary structure of a protein. (In eukaryotes, the primary RNA transcript must undergo RNA processing to become mRNA.)