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52 Cards in this Set

  • Front
  • Back

Biological change that occurs according to time cycles

Circadian rhythm

Opposite of inhibited

Disinhibitation

Drug that induces sleep

Hypnotic

Condition characterized by difficulty falling asleep, staying asleep, or both

Insomnia

Hormone that is released by the pineal gland that makes a person feel drowsy

Melatonin

Stages 1 through 4 of the sleep cycle

Non rem sleep

Condition associated with excessive sleep that ollows long-term insomina or the use of drugs that depress REM and non-REM sleep

Rebound hypersomnia

The stage of sleep when dreaming occurs

Rapid eye movement sleep

Drug that causes relaxation and promotes drowsiness

rapid eye movement sleep

drug that causes relaxation and promotes drowsiness

sedative

drug that increases activity in the brain and is used to treat ADHD and narcolepsy

stimulant

drug whose effect mimics the effects produced by stimulation of the sympathetic nervous system

sympathomimetic

this form of sleep lasts 90-110 mins

REM sleep

chronic illnesses that can interfere with sleep are ga____________ re____ d______, a_____, and ch_____ p____, among others

gastroesophageal reflux disorder, angina, chronic pain

factors that contribute to inability to get sleep are sl___ a____, re______ l___ sy_____, ca______ near bed time, use of d____, ch____ i______

sleep apnea, restless leg syndrome, caffiene , drugs, chronic illness

insomnia affects ___ of the world population

1/3

_% of Canadians have been diagnosed with sleep apnea

3%

___% of those with sleep apnea reported symptoms of high risk for sleep apnea

25%

sleep apnea increases risk for ca___________ d______

cardiovascular disorders

sleep apnea can last between ____ and ____

few seconds and 30 mins

drugs alter n__-___ and ___ sleep, which can result in r______ h__________ and increased dreaming once the drugs are discontinued

non-rem, rem, rebound hypersomnia

barbituates dose effects:


N_____ -> D_____ A____, -> Di_____ -> Se_____, -> H_____, -> G______ A__________, -> C___, -> D____

Norma, Decreased anxiety, Disinhibition, Sedation, Hypnosis, General Anesthesia, Coma, Death

B_________ have largely replaced b_______ for treatment of insomnia

Benzodiazepines, Barbiturates

A benzo like drug called z________ is a b______ c______ release formulation, food ______ absorption

zolpidem, biphasic controlled, reduces

zaleplon, zolpidem, eszopiclone, and zopiclone modulate the _______ receptor _______ channel, and are similar to benzo's

GABA-A, chloride

it is claimed that z______ and z______ have less disruption of ___ and ___-___ sleep

zaleplon, zolpidem, rem, non-rem

di____________ and do_____ are OTC used for short term relief of insomnia, both have been used by women, and are pregnancy catagory _

diphenhydramine, doxylamine, B

a__________ should be avoided in men who have benign p______ h__________ and they may reduce the m___ s______ of _____________ w_____

antihistamines, prostate hypertrophy, milk supply of breastfeeding women

natural remedies for sleep are ________ and _______ ____

melatonin and valerian root

most of the misc insomnia agents are controlled except for __________

ramelteon

it is believed that drugs for narcolepsy stimulate ____-________ receptor sites

alpha-adrenergic

(narcolepsy) a________ and m___________ are stimulants classified as s____________

amphetamine andmethylphenidate, sympathomimetics

a sympathomimetic mimics effects produced by stimulation of the _________ n_____ s_______

sympathetic nervous system

the most commmon adverse effects produced by armodafinil and modafinil are h_____, n______, i_____ and d______ (narcolepsy)

headache, nausea, insomnia, dizziness

______-______ syndrome, a fatal drug rash, has been linked to ________ use (narcolepsy)

stevens-johnson, modafinil

modafinil shoudl have these warning labels, a____ a________, may d_____ effect of o___ c__________, may be h____ f______

avoid alcohol, may decrease the effect of oral contraceptives, may be habit forming

three subtypes of ADHD are pr_________ h______-i______, pr______ i_______, and c_____ t___

predominantely hyperactive-impulsive predominantely inattentive, combined type

d______ occurs in about __% to __% of children with ADHD

dyslexia, 20-30%

______ is most strongly linked to a cause for ADHD

genetics

c_______ s____ and a_____ during pregnancy has shown to increase the risk for ADHD

cigarette smoke, alcohol

exposure to l___ is a risk factor for ADHD

lead

parts of the brain affected by ADHD are the f_____ l____ of the c_______ and the b____ _______

frontal lobes of the cerabelum and the basil ganglia

can medication cure ADHD?

No, it can only control symptoms

the most effective therapy for ADHD involves drug treatment in addition to b________ t______

behavioral therapy

pharmaceutical treatment of ADHD is achieved with the administration of ________ and ______________ stimulants

amphetamine and nonamphetamine

rather then _______ hyperactivity, ADHD patients who take amphetamine stimulants show an _________ unlike people without ADHD

increase, decrease

amphetamines are sympathomimetics structually similar to n__________ (ADHD)

norepinephrine

amphetamines block ____, stimulate release of n___________, and stimulate release of d______ (ADHD)

MAO, norepinephrine, dopamine

a non-amphetamine stimulant is a___________, which inhibits the reuptake of n__________ (ADHD)

atomoxetine, norepinephrine

common side effects produced by amphetamines are d______ a_____, n_____, s____-a___, a_____ and i______ and they can also cause in______ (ADHD)

decreased appetite, nausea, stomach-ache, anxiety and irritability, also insomnia

Doses greater then therapeutic doses of amphetamines can produce a________ s______, a type of drug-induced psychosis (ADHD)

amphetamine syndrome

_________ have a high abuse potential, and are controlled substances, a________ however is not (ADHD)

amphetamines, atomoxetine