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10 Cards in this Set
- Front
- Back
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microorganism become resistant to drugs not people |
principles of antimicrobial therapy |
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Source of bacteria antibotics |
steptomyces and bacillus species |
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antibotics source for fungal molds |
Penicillium and Cephalosporium |
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Broad spectrum antibotics |
disadvantage in that may normal microbiota are also destroyed and competition is eliminated for some potential pathogens that are part of the normal human microbiota |
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testing or drug susceptibiliy in the lab: Kirby-Bauer Procedure |
discs are soaked in a chemical then placed then placed on a previusly inoculated agar plate. after incubation, zones of inhibition are measred giving the minimum inhibitory concentration or Mic |
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a drug is selectively toxic if it harms the pathogen but not host |
selective toxicity |
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differences from eukaryotic human cells |
bacterial pthogens |
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difficult to treat because cells of pathogens are similar to human cells |
eukaryotic pathogens |
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inside the cell |
viral pathogens |
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mechanism of drug action upon the bacterial cell |
1. Call wall synthesis 2. Nucleic acid structure and function 3. protein synthesis 4. cell membrane structure of function 5. folic acid synthesis |
