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12 Cards in this Set
- Front
- Back
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Alcohol consumption Related cancers
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oral cavity, pharynx, hypopharynx, larynx, esophagus, and liver
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Cigarette/alcohol How does it increase risk of cancer
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ethanol > ADH(MEOS) > Acetaldehyde (DNA Damage) > ALDH > Acetate
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Xenobiotics
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Toxic, mutagenic, and carcinogenic chemicals in food
Activated by phase I activation enzymes Defense mechanisms Phase II detoxification enzymes |
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adipose tissue
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releases free fatty acids
Increased free fatty acids gives rise to insulin resistance and causes chronic hyperinsulinemia Correlates with colon, breast, pancreatic, and endometrial cancers |
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Syndrome of cachexia
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Most severe form of malnutrition
Present in 80% of cancer patients at death Anorexia, early satiety, weight loss, anemia, asthenia, taste alterations, and altered protein, lipid, and carbohydrate metabolism |
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Paraneoplastic syndromes
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Symptom complexes that cannot be explained by the local or distant spread of the tumor or by the effects of hormones released by the tissue from which the tumor arose
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Chemotherapy
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Eliminate enough tumor cells so the body’s defense can eradicate any remaining cells
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Ionizing radiation
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Eradicate cancer without excessive toxicity
Avoid damage to normal structures Ionizing radiation damages the cancer cell’s DNA |
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Debulking surgery
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removal of part of a malignant tumour which cannot be completely excised, so as to enhance the effectiveness of radiation
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Tobacco Is linked to what cancers
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lung, lower urinary tract, aerodigestive tract, liver, kidney, pancreas, cervix uteri
Linked to myeloid leukemia |
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Bystander effects
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innocent cells
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Radon
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derived from radioactive decay of uranium, can be trapped in homes and is carcinogenig to humans.
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