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18 Cards in this Set

  • Front
  • Back
Vascular Response
-the blood vessels around the injured area constrict briefly
-dilate as chemical mediators
-blood flow to the injured area increases=redness and warmth
-raises hydrostatic pessure (capilarry pressure)
-result: edema at the site and dilution of the organisms or toxins
Cellular Response
WBCs move into the area as blood flow increases to the injured tissues
-neutophils and macrophages ingest harmful bacteria and dead tissue cells (phagocytosis)

-neutrophils arrive within 90 mins
-^move from inside the capillary to the injured tissue: diapedesis
Healing and tissue repair
-macrophages clean up site for healing
-new cells are reproduced to replace the functional tissue
-if regeneration is impossible, collagen scar replaces the destroyed tissue
Inflammatory Changes in the Older Adults
-thinner, drier, and more fragile
-decreased blood flow
Acute inflammation
-short-term reactions
-last for 1-2 weeks
systematic manisfestation
fever, tachycardia, increased respiratory rate, loss of appetite, fatigue, enlarged lymph nods, WBC count > 10,000/ mm3
management of acute inflammation
-wound care
-encourage rest
-eat a well-balanced diet, high in carbohydrates and protein with vitamins supplements and extra fluids
-receive anti-inflammatory medications, antibiotics, corticosteroids
-apply cold or heat theraphy
-elevate inflamed area
-A, C, E - antioxidants- get rid of your free radicals
-zinc helps tissue healing
Diagnostic Tests
-WBC count with differential
-Erythrocyte sedimentation rate (generalized inflammation)
-c-reactive protein (CRP): active inflammation and tissue necrosis (quicker)-->rheumatic heart disease, IHDS,generative joint disease, etc.
-cultures of wound, blood, or other infected body fluids: determine the cause of the inflammation; collect sputum, urine, feces, etc
-sensitivity studies
-Lumbar puncture (prawn aka fetal position)
-ultrasound examination
WBC
-4500-10,000 per mm^3
-leukocytosis: acute infection, tissue necrosis, trauma, stress
-leukopenia: anemia, viral infections, autoimmune disease, HIV, cancer
neutrophils
-55-70%
-neutrophilia: acute infection, inflammatory diseases
-neutropenia
Eosinophils
1-3%
allergies, parasitic dieases,
Pathogenic Organisms
bacteria, mycoplasma
intial stage
incubation period; bacteria grows
prodromal stage
symptom stage
acute stage
pathogen reproduction and increasing manifestation
convaslescent stage
pathogen destruction and tissue repair
resolution
healing of infection
Antibiotic Resistant microorganisms
-MRSA: vancomycin
-VRE
-PRSP:
-CDAD: vancomycin + flagyl