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19 Cards in this Set
- Front
- Back
- 3rd side (hint)
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WHAT IS REMICADE USED FOR
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rheumatoid arthritis, crohn's disease, anti-TNF
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what is Rituxan used for
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treatment of lymphoma, cell surface antigen on B cells, pre-B cells
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what are the monoclonal antibodies used as therapeutics
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remicade
rituxan herceptin |
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what is herceptin used for
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cancer
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what does papain do to antibodies
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results in 2 Fab and a Fc
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what does pepsin do to antibodies
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results in Fab2 and a Fc
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what are hybridomas
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antibody forming cell fused w/ tumor cell
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how are monoclonal antibodies generated
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immunize mouse to stimulate antibody production
fuse antibody forming cell w/ tumor cell hybridomas screened for antibody production clone antibody producing hybridomas monoclonal antibodies isolated and cultivated |
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what are the commercial advantages of PEGylated drugs
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oppurtunities for new delivery formats and dosing regimes
extended patent life of previously approved drug |
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what is PEGASYS used for
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treatment of hep C
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what is PEG-Intron used for
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chronic hep C
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what is Oncaspar used for
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treatment of acute lymphoblastic leukemia for patients that are hypersensitive to L-asparaginase
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what is Neulasta used for
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sever cancer chemotherapy induced neutropenia
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what is Doxil used for
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treatment of Cancer
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what is PEGylated liposome
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Doxil
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containing doxorubicin
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what is PEGylated recombinant methionyl human granulocyte colony stimulating factor
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neulasta
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what is PEGylated L-asparaginase
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Oncaspar
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what is PEGylated alpha-interferons
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PEG-Intron
PEGASYS |
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what are the successful examples of pegylation
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PEG-Intron
Neulasta Doxil PEGASYS Oncaspar |
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