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20 Cards in this Set
- Front
- Back
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what is the Transdermal Drug Delivery system
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drug delivery systems that facilitate the passage of therapeutic quantities of drug of interest through the skin and into the systemic circulation
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what are the common features of TTS
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controlled release patch
adhered onto skin (non invasive) absorption through skin barrier reaches systemic circulation to maintain constant plasma level of drug for intended duration for systemic effects |
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what are the characteristics of CR dosage forms
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both release and intended duration are defined
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what are the ADVANTAGES OF TTS (CR)
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-eliminating peak and trough profile
-reducing dosing frequency of drugs with short half life -maintaining controlled level for drugs with small TI (MTC/MEC) -free of GI irritation and eliminating problems of drug degredation in gastric fluid -reducing drug metabolism from 1st pass effect (bypassing portal circulation) -easy to discontinue (be aware of SC reservoir) |
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what was the 1st TTS product
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scopolamine
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what are the properties of scopolamine
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1st TTS product
circular, flat, capsule type w/ PRIMING DOSE for antimotion sickness/nausea/sedative placed in POST AURICULAR AREA 15mg residual dose (1mg/3 days) |
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what dosage form is transderm-nitro
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capsule
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what dosage form is nitro-disc
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microseal matrix
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what dosage form is nitro-dur
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matrix
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what dosage form is nitroderm
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matrix
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what dosage form is deponit
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matrix
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what is nitroglycerin patch used for and what are the characteristics
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24 hr release
prophylaxis of angina pectoris |
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what are advantages of scopolamine patch vs oral
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seperates therapeutic effect from unwanted peripheral effects (CNS effects/drowsiness/dry mouth)
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what is Clonidine
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reservoir design, square in shape
antihypertensive/pain off label use of low dose for ADHD may cause burns during MRI itching and erythmea |
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WHAT IS A CENTRALLY ACTING ALPHA 2 ADRENERGIC AGONIST
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clonodine
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what is Estradiol/Progestin or Estrdiol only used to treat
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treatment of:
vasomotor symptoms associated to menapose birth control prevention of post menopasol osteoporosis |
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what is Fentanyl for
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potent opioid analgesic for management of chronic pain
DURAGESIC |
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what are nicotine patches
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nicoderm
habitrol prostep nicotrol |
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what are the testosterone patches and what are they used for
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testoderm
androderm for primary male hypogonadism or hyponadotropic hypogonadism |
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what is Oxybutynin
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OXYTROL
antipasmodic/anticholinergic agent racemic mixture of R and S indicated for overactive bladder |
