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21 Cards in this Set

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Vestibulocerebellum = ?

effect of lesion
Flocculo-nodular lobe = concerned with maintaining equilibrium + adjustment of anti-gravity muscles during movement.

lesion = Disequilibrium – movement relative to gravity.
Spinocerebellum = ?

effect of lesion
Anterior lobe + Vermis of Posterior lobe = postural reflexes; integration of axial and limb musculature with proper equilibrium.

lesion = Ataxia – discoordination of gait and/or reaching.
Neocerebellum = ?

effect of lesion
Pontocerebellum = voluntary movement, smoothing fine voluntary movements of distal musculature on top of proper equilibrium and posture.

lesion = Intention Tremor; Dysmetria - problems targeting with arms or legs; cognitive and emotional discoordination
5 cell types of cerebellum?
Granule Cells
Purkinje Cells
Golgi Cells
Basket Cells
Stellate Cells
Input Fiber Types of cerebellum
Climbing Fibers
(Inferior Olive)

Mossy Fibers
(All others, eg. Pons)
output fiber type of cerebellum
Purkinje Cell
only excitatory neuron of cerebellar cortex?
granule cells
Vestibulocerebellum:

Inputs?
Outputs?
Inputs = Vestibular apparatus via vestibular nerve fibers; enter via ICP

Outputs = Fastigial nucleus to vestibular nuclei
*Regulate vestibulospinal tract
Spinocerebellum:

Inputs?
outputs?
Inputs = Muscle spindles and GTOs to spinocerebellar or cuneocerebellar tracts; enter via ICP or SCP

Outputs = Globose + emboliform nuclei to contralateral red nucleus via SCP
*Regulate rubrospinal tract
Neocerebellum:

Inputs?
Outputs?
Inputs = From all sensory modalities after processing in cerebral cortex; Collaterals of corticospinal tract → pontine nuclei → contralateral cerebellum via MCP

Outputs = Dentate nucleus to contralateral VL via SCP → fibers project to motor + premotor cortices
*Regulate corticospinal tract
Inferior Cerebellar Peduncle (ICP) Afferents
Afferents: Clarkes Column (Dorsal Spinocerebellar Tract), External Cuneate Nucleus (Cuneocerebellar Fibers), Spinal Nuc V (Trigeminocerebellar), Inferior Olive, Reticular Formation, Vestibular Nucleus & Vestibular Nerve.
Inferior Cerebellar Peduncle (ICP) Efferents?
Efferents to Vestibular Nuc & Reticular Form from Fastigial & Vestibulocerebellum.
Middle Cerebellar Peduncle (MCP) Afferents
Afferents from the Pontine Nuclei.
Middle Cerebellar Peduncle (MCP) efferents
none
Superior Cerebellar Peduncle (SCP) Afferents ?
Afferents from Spinal Cord - Ventral Spinocerebellar Tract
Superior Cerebellar Peduncle (SCP) Efferents ?
Efferents to Red Nucleus & VA/VL of Thalamus (dentatorubrothalamic tract)
Peripheral Nerve Transection causes
Flaccid paralysis with atrophy
Spinal Cord Transection causes
paralysis with hyperreflexia and no atrophy
pyramidal syndrome - motor cortex causes
moderate contralateral hemiparesis, hyperreflexia, spasicity
pyramidal syndrome - internal capsule
dense contralateral hemiparesis, hyperreflexia, spasicity
extrapyramidal syndrome - basal ganglia
Involuntary Movements, Tremor, Dystonia & Akinesia