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27 Cards in this Set
- Front
- Back
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Cephalothin
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1
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Cephalothin
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1
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Cefazolin
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1
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Cephalexin
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1Oral
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Cefadroxil
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1Oral
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Cefamandole
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2
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Cefuroxime
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2oral
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Cefaclor
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2oral
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Cefoxitin
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2Anaerobes
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Cephalothin
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1
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Cefazolin
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1
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Cephalexin
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1 Oral
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Cefadroxil
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1 Oral
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Cefamandole
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2
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Cefuroxime
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2 Oral
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Cefaclor
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2 Oral
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Cefoxitin
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2 Anaerobes
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Cefotaxime
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3
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Cetriaxone
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3 Best CNS Penetration, covers bacterial meningitis and N. gonorrhea
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Ceftrazidime
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3
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Ceftazidime
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3
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Cefepime
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4
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First Generation
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S. aureus and streptococci
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Second Generation
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S. aureus and streptococci
+ E. coli, klebsiella, haemophilus, proteus |
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Third Generation
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S aureus and streptococci
+ E. coli, klebsiella, haemophilus, proteus + Enterobacter, Pseudomonas, Seratia, Klebsiella - Lose some gram + power |
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Fourth Generation
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S. aureus, streptococci
+ E. Coli, Klebsiella, Haemophilus, Proteus + Enterobacter, Pseudomonas, Seratia, Klebsiella + added muscle against gram + and pseudomonas |
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Pharmacokinetics of PCNS and Cephalosporins
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Binds to tissue and antimicrobial effect can persist after blood levels fall.
Low concentration in ocular fluid and CSF. Cross placenta into fetal circulationBind plasma albumin to varying degrees (recommended doses already take this into account) |
