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17 Cards in this Set
- Front
- Back
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Cephalosporin MOA
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Inhibit bacterial cell wall synthesis
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Cephalosporin CSF Penetration?
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POOR CSF Penetration- not recommended for meningitis
Cefuroxime has some CSF penetration |
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What are 1st Gen Cephalosporins?
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Cefazolin, Cephalexin, Cefadroxil, Cephradine
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What are 1st Gen Cephalosporin routes?
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Cefazolin (IV), Cephalexin (PO), Cefadroxil (PO), Cephradine(PO)
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What are 2nd Gen Cephalosporins ?
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Cefuroxime, Cefaclor, Cefprozil, Loracarbef
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What are 2nd Gen Cephalosporin routes ?
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Cefuroxime (IV), Cefaclor (PO), Cefprozil (PO), Loracarbef (PO)
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Unique about Cefuroximine?
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Some CSF penetration
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Name the Anaerobic Cephalosporins ?
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Cefoxitin (IV), Cefotetan (IV)
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Unique about Cefotetan?
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Increased risk of Bleed (do not give if on Warfarin) Vit K recommended
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Name the 3rd Gen PO Cephalosporins?
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Cefdinir (PO), Cefditoren (PO), Cefiximev, Cefpodoxime (PO), Ceftibutin (PO)
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Name the Standard 3rd Gen Cephalosporins
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Cefotaxime, Ceftizoxime, Ceftriaxone
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What is unique about 3rd Gen Cephalosporins?
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Good CSF penetration
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What is unique about ceftriaxone?
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hepatic elimination, no renal adj
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Anti-Pseudo cephalosporins
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Ceftazidime, Cefepime, Ceftobiprole, Ceftaroline
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Anti-Pseudo good for CNS infections?
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Ceftazidime
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Ceftobiprole
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SSTI infections, covers MRSA
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Ceftaroline
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covers MRSA
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