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82 Cards in this Set

  • Front
  • Back

What are the functions of the frontal lobe?

motor control


judgement


impulsivity


problem solving


social interaction




Broca's area

What are the functions of the occipital lobe?

visual cortex




(blind sight)

What are the functions of the temporal lobe?

spirituality


contains the limbic system and auditory system




wernick's area

What are the functions of the cerebellum?

coordinates movement


precision


accurate timing

What are the functions of the hypothalamus?

works with the ANS


thirst/hunger


rage/pleasure

What are the functions of the hippocampus?

memory and learning

What are the functions of the amygdala?

emotions!


empathy


fear/aggression




activated by mirror neurons


(part of the limbic system)

What are the functions of the nucleus accumbens?

pleasure centre


(matures faster than the prefrontal cortex)

What are the functions of the left side of the brain?

organization


math skills


logic


spoken language


word recognition


literal interpretation





What are the functions of the right side of the brain?

creativity


non verbal


face recognition


spacial relations


multitasking


perceptual tasks

What is GABA? How does it work?

an inhibitory amino acid neurotransmitter in the brain



when GABA attaches to its receptor on the post synaptic neuron, it allows Cl- to pass through.


--it hyperpolarizes the post synaptic neuron


--inhibits the transmission of an impulse

What is Glutamate?

an excitatory amino acid neurotransmitter


depolarizes AP in the spinal cord

What is Glycine? How does it work?

it is an inhibitory CNS neurotransmitter




when Glycine attaches to its receptor on the post synaptic neuron, it allows Cl- to pass through.--it hyperpolarizes the post synaptic neuron--inhibits the transmission of an impulse

What does NE regulate in the CNS?

arousal




mood




blood pressure control

What does Serotonin regulate in the CNS?

mood




sexual function




appetite




sleep

What 2 ways can antidepressants work?

Either block the break down of serotonin or blocks serotonin from leaving the synaptic cleft

What is schizophrenia likely caused by>

imbalance of dopamine

What is oxytocin and what does it do?

a hormone released from the posterior pituitary gland




plays a role in the formation of monogamous relations, trust and attachment

high levels of oxytocin causes what?

high levels of trust and attachment

How does alcohol effect GABA in the CNS?

since GABA is an inhibitory neurotransmitter, when alcohol is consumed it blocks this receptor and hyper polarizes its affects


--causing heightened GABA effects


-----sedation, incoordination

How does alcohol effect Glutamate in the CNS?

Since glutamate is an excitatory neurotransmitter, the attachment of alcohol causes the effects of Glutamate to be suppressed


----memory loss, cognitive dysfunction

How does alcohol effect 5HT in the CNS?

Since serotonin is an excitatory neurotransmitter, the attachment of alcohol blocks the effects of 5HT


---agression, sleepiness, impulsiveness

What do Barbiturates and Benzodiazepines do?

cause sedation and sleepiness

What does cocaine do to the CNS?

blocks re-uptake of dopamine, NE, E to the presynaptic terminal

What are amphetamines? What do they do?

-they are a stimulant


-block the release of dopamine, from the axon


terminals and block the re-uptake of dopamine



What are the short term effects of


amphetamines?

increased HR


increased food pressure


reduced appetite


dilation of the pupil


feeling of happiness and power


reduced fatigue

What is the main ingredient of marijuana?

tetrahydrocannabinol (THC)

Where in the brain does tetrahydrocannabinol localize

in the limbic system cortex, hippocampus,


cerebellum

What are the symptoms of heroin?

analgesia (reduced pain)


euphoria


nausea


sedation


reduced anxiety


hypothermia


reduced respiration (suppresses preBotC)


reduces coughing



What does preBotC do?

stops breathing


-regulates breathing patterns

What disorder does cocaine and


methamphetamines mimic?

schizophrenia, paranoia, compulsive behaviour

What disorder does stimulates mimic?

anxiety, panic attacks, mania, and sleep disorders

What disorder does LSD, ecstasy and psychedelics mimic?

delusions and hallucinations

What disorder does alcohol, sedatives and narcotics mimic?

depression and mood disturbances


What are neurodegenerative diseases?

diseases that lead to neural death


progressive loss of structure and function

what are the most common neurodegenerative diseases?

parkinsons


alzheimers


huntingtons


ALS

what are the diseases of the cerebral cortex?

alzheimers

what are the diseases of the basal ganglia?

Parkinsons

Huntingtons



what are the diseases of the cerebellum?

Ataxia


Spinocerebellar atrophy

what are the diseases of the motor neurons and spinal cord?

ALS


spinal muscular atrophy

What is the most common cause of dementia?

alzheimers

What are symptoms of alzheimer's disease?

loss of memory,


task performance,


speech


recognition of persons

What is deteriorating that causes alzheimer's?

loss of the cholinergic neutrons in the basil


forebrain, hippocampus, frontal and parietal


cortex


plague and tangles

What are the risk factors for dementia?

age


genetics


atherosclerosis


high cholesterol


diabetes


down syndrome

What are the symptoms of Parkinson's disease?

rigidity


involuntary movements


shuffling gait



What are the treatment options for Parkinson's disease?

stop the breakdown of dopamine


DBS- tries to mimic the activity of dopamine (works on Tourettes too)

How is huntington's disease inherited?

by one parent on chromosome 4

What are the symptoms of ALS?

selective motor neuron loss

effects muscle control, paralysis


no cure (more common in males)

What is EEG?

electroencephalogram


non-invasive technique for detecting and localizing electrical activities of the CNS


-uses electrodes

What is EEG used for?

localizing epilepsy


for research to analyze cognitive functions of the brain

How does the EEG work?

generated signals from the cortex


measures inhibitory and excitatory APs

What is REM sleep?

dreams occur


low amplitude, high frequency


eyes flicker


similar to wakefulness (beta waves)

What is NREM?

high amplitude, low frequency (delta waves)

What is REM behaviour disorder

movement of muscles while sleeping


(not normal- muscles should be flaccid)


--early indication that neutrons are dying

What is the reticular activating system?

a system that regulates sleep and wakefulness


-plays major role in alertness, fatigue, and


motivation to perform various tasks

What is the reticular activating system connected to?

thalamus


hypothalamus


cortex

What is the ventrolateral preoptic nucleus?

-in the hypothalamus


-PROMOTES SLEEP


-primarily active during sleep and inhibit other neurons involved in wakefulness


-destruction of this area can result in insomnia, coma and eventually death

What are the two types of stroke?

hemorrhagic stroke (15%)


ischemic stroke (85%)

What is hemorrhagic stroke?

bursting of a blood vessel

What is a ischemic stroke?

blood clot or blocked vessel

What is a carotid ultrasound?

will show narrowing of a blood vessel in the carotid artery

What is multiple sclerosis?

wen your immune system attacks myelin and


oligodendrocytes in the CNS

What are the symptoms of multiple sclerosis?

blurred vision


numbness


incoordination


speech disturbances





Is MS more common in men or women?

women

Why does removing of the myelin cause such big problems in MS?

action potentials on the axons are slowed


What are the three types of pain?

Nociceptive pain


inflammatory pain


pathological pain

What is nociceptive pain?

touching something hot, cold, intense, chemical irritant that sends a noxious stimuli that causes an autonomic withdrawal reflex


-high-threshold pain

What is inflammatory pain?

associated with tissue damage, causing inflammation and the activation of macrophages, etc


-low-threshold pain

What is pathological pain?

separates into neuropathic pain and dysfunctional pain


-neuropathic pain- damage to the nervous


system


-dysfunctional pain- abnormal function

What are the functions of the spinal cord?

-conduction- of signals throughout the body


-locomotion- of muscles- repetitive, coordinated actions


reflexes- involuntary responses to stimuli, involving brain, spinal cord, and peripheral nerves

What is the white matter in the spinal cord?

bundles of axons


fibres that go up and down the spinal cord

What is spina bifida?

congenital defect in which one or more vertebrae fail to form a complete vertebral arch for enclosures of the spinal cord


-common in the lumbosacral region

Why doesn't regrowth happen in the central nervous system?

there are oligiodendrites in the CNS that have proteins in them that stop axon growth

What is sensory memory?

holds sensations




lasts up to 1/2 a second for visual and 2-4 seconds for auditory

What is short-term memory?

holds perceptions for analysis




up to 30 seconds without rehearsal

what is long-term memory?

relatively permanent storage




relatively permanent

What is responsible for the formation of new memories?

the hippocampus

What is retrograde amnesia?

can't remember things that happened before a certain point

What is anterograde amnesia?

can't form new memories past a certain point

When does long-term potentiation occur?

occurs when one or more axons bombard a dendrite with stimulation

What does long-term potentiation do?

changes the strength of synapse


(can increase or decrease the number of receptors on an axon terminal)

What does long-term potentiation activate?

NMDA (glutamate receptor)


if you block NMDA, you block LTP receptors