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15 Cards in this Set
- Front
- Back
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Where do all lymphocytes arise from?
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Bone marrow stem cells
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Where do T cells mature?
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Thymus
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What do B cells mediate?
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Humoral immunity
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What is humoral immunity?
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Involvement of Antibodies
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What do t cells mediate?
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Cell mediated immunity
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Where do b and t cells cells compartmentalise?
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in lymhoid tissue
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What organ has no lymphoid drainage?
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Spleen
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What can T and B cells be?
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Morphologically small lymphocytes (inactive -- naive or memory cells)
or lymphoblasts (active) |
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What is the terminal stage of B-cell differentiation?
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Plasma cell
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What do plasma cells secrete?
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Immunoglobulins
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How can we detect t and b cells
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flow cytometry
tissue immunofluorescence Immunohistochemistry |
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What allows us to detect t and b cells with anti sera?
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Unique surface molecules.
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What do lymphocytes recirculate through?
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Lymph vessels and blood
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What does lymphocyte recirculation allow?
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immune survellience
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How do blood vessels know their location in the blood circulation?
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Expression of vascular addressins by HEVs that interact with lymphocyte homing receptors.
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