Cells And Organelles

Front 1

Define a cell

Back 1

A basic unit of an organism, consisting of an aqueous solution and organic molecules

Front 2

List major organelles

Back 2

Nucleus
Plasma membrane
Cytoskeleton
Cillia & flagellum
Ribosome
Endoplasmic reticulum
Golgi complex
Lysosome
Peroxisome
Proteasome
Mitochondria

Front 3

Plasma Membrane

Structure:
Function:

Back 3

Plasma Membrane

Structure: Fluid Mosaic model, Phospholipids, cholesterol, glycoclipids, proteins
Function: Transport, Channels, Communication, Gradients, connections

Front 4

Cytoskeleton

Structure:
Function:

Back 4

Cytoskeleton

Structure: Intermediate Filaments, Microfilaments, Microtubules
Function: Shape and organisation, movement
MTs in Cillia/flagellum
IF-Keratin

Front 5

Cillia & Flagellum

Structure:
Function:

Back 5

Cillia & Flagellum

Structure:
Function:Move fluid over cell surface
Move cell

Front 6

Nucleus

Structure:
Function:

Back 6

Nucleus

Structure: Membrane supported by lamins, pored, chromatin, DNA, mRNA, Primary RNA
Function: Container of genomic information

Front 7

Ribosome

Structure:
Function:

Back 7

Ribosome

Structure: 70s and 80s
Function: Protein syntheis

Front 8

Endoplasmic Reticulum (Rough)

Structure:
Function:

Back 8

Endoplasmic Reticulum (Rough)

Structure: Ribosome covered attached to nuclear membrane
Function: Synthesizes glycoproteins & phospholipids-->Cell organelles or PM

Front 9

Endoplasmic Reticulum (Smooth)

Structure:
Function:

Back 9

Endoplasmic Reticulum (Smooth)

Structure:
Function: Synthesizes fatty acids and steroids, detox drugs G6P and G6-P
Estrogen, testosterone. In liver the ER changes, gain more ER and enzymes. Higher doses increase

Front 10

Golgi Complex

Structure:
Function:

Back 10

Golgi Complex

Structure: 3-20 flattened sac, cisternae, cis, trans
Function: Cis from ER, Med-GPs, glycolipids, lipoproteins, exit

Front 11

Lysosome

Structure:
Function:

Back 11

Lysosome

Structure: Vesicle, digestive enzymes
Function: Autophagy, autolysis, endosomes, pushy vesicles

Front 12

Peroxisome

Structure:
Function:

Back 12

Peroxisome

Structure: Peroxidase, oxidase
Function: Deal with oxidation of AAs, FAs, alcohol -->h2o2-->catalase-->safe

Front 13

Proteasome

Structure:
Function:

Back 13

Proteasome

Structure: 4 stacked rings around a central core
Function: normal protein metabolism/degradation

Front 14

Mitochondria

Structure:
Function:

Back 14

Mitochondria

Structure: ATP production, 2 membranes, genes separate from nucleus-maternal
Function: Cell injury/stress-->Bcl2-->CytC-->Caspase-->Apoptosis

Front 15

What are the different types of Cell junctions and comment on them?

Back 15

Adherens junction: connection between Epidermal cells
Tight junction: Strong, prevent passage of molecules between cells. seal
Desmosome junction: Tensile strength and integrity
Hemidesmosome junction: Dermis to epidermis
Gap junction: Ions & 2nd messengers

Front 16

List some diseases of the following:

Mitochondria
Lysosomes
Microtubules
GAP junctions
IFs hemidesmosmes

Back 16

List some diseases of the following:

Mitochondria : Mito cytopathy, Ox phosphorylation
Lysosomes: Tay Sachs - storage disease-neuron death
Microubules: kartagener (dynein) syndrome: immotile cillia
GAP junctions: Cx26 non sensorineural deafness
IFs hemidesmosmes: Epidermolysis bullosa simplex