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35 Cards in this Set

  • Front
  • Back
What are the 2 divisions of the circulatory system?
1. Lymphatic
2. Cardiovascular
Are arteries efferent or afferent vessels?
Efferent
What is the route of blood for elastic arteries?
From the heart to major regions of the body
What are the 3 efferent vessels in the body?
Elastic arteries, muscular arteries and arterioles
What are the afferent vessels in the body?
Venules, medium veins, large veins
What are the 3 tunics found in the body?
1. Tunica intima
2. Tunica media
3. Tunica adventitia
Describe the characteristics of the tunica intima (inner coat).
-formed of endothelium, subendothelial layer of CT and sometimes, an internal elastic lamina.
What type of epithelium makes up the endothelium?
Simple squamous epithelium, supported by a basal lamina
What is the subendothelium composed of?
It is scattered with smooth muscle cells that produce the CT fibers and matrix of this layer
What is the composition of the internal elastic lamina?
It is a sheet of elastin with fenestrae that allow materials to diffuse deep into the vessel wall.
What is the function of elastic arteries and name some examples of elastic arteries.
Conduct blood from heart. Aorta, brachiocephalic, common carotids, subclavians, common iliacs
Describe the tunica intima of elastic arteries
-Thick
-No distinct internal elastic lamina
Describe the tunica media of elastic arteries
-40-70 elastic laminae
-Alternating smooth muscle cells
-reticular fibers
-Proteoglycans
-Glycoproteins
-No distinct external elastic lamina
Describe the tunica adventitia of elastic arteries
-Thin and unremarkable except for large vasa vasorum
What is the function of muscular arteries and name some examples.
Distribute blood to specific body regions. Named to specific body region (axillary, brachial, radial, ulnar, femoral, etc)
Describe the tunica intima of muscular arteries.
-Thin
-Smooth muscle cells
-Prominent internal elastic lamina
Describe the tunica media of muscular arteries.
-3-40 layers of helically oriented smooth muscle cells (contraction regulates blood flow)
-Elastic lamellae
-External elastic lamina (in larger vessels)
Describe the tunica adventitia of muscular arteries.
-Thick
Describe the characteristics of arterioles.
-Branches of small muscular arteries
-Diameter <0.5 mm
-Branch into metarterioles
-Metarterioles lead to capillary bed
Describe the tunica intima of arterioles.
-Thin
-Internal elastic lamina
Describe the tunica media of arterioles.
-1-2 layers of circular smooth muscle cells
-No external elastic lamina
Describe the tunica adventitia of arterioles.
-Thin
Describe the tunica media of metarterioles.
-Discontinuous smooth muscle cells.
What is an arteriovenous anastomoses?
In some tissues, like skeletal muscle and the skin of hands and feet, arterioles bypass capillary beds and divert blood directly into venules.
What is the function of arterioles?
To control blood flow to capillary bed
Describe capillaries
-Arterioles branch into capillaries
-7-9 micrometers in diameter
-Tunica intima: endothelium, basal lamina.
-Tunica media: intermittent pericytes.
-Thin tunica adventitia is sometimes visible.
What is a pericyte?
-Derived from mesenchyme and contain contractile proteins (actin, myosin, and tropomyosin)
What is the function of a pericyte?
-It contracts to control blood flow through the capillary and participate in their repair following vascular injury.
What are the 4 types of capillaries?
1. Continuous (somatic)
2. Fenestrated (visceral) with diaphragms
3. Fenestrated without diaphragms
4. Discontinuous, sinusoidal
Where are continuous(somatic) capillaries found?
Muscle tissue, exocrine glands, CT, nervous tissue.
Where are fenestrated(visceral) with diaphragm capillaries found?
Kidney, intestine, endocrine glands
Where are fenestrated without diaphragm capillaries found?
Renal glomerulus
Where are discontinuous, sinusoidal capillaries found?
Spleen, liver, bone marrow
What are the characteristics of continuous (somatic) capillaries?
-Highly impermeable
-Continuous endothelium
-Tight junctions
-Complete basal lamina
-Pinocytotic vesicles ferry macromolecules bi-directionally (except in CNS)
-It forms the blood brain barrier
Describe the characteristics of fenestrated (visceral) capillaries.
-More permeable
-Fenestrated endothelium
-Complete BL
-Diaphragms present