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4 Cards in this Set

  • Front
  • Back

Types of gangrene

1. Coagulative necrosis2. Liquefaction necrosis3. Gangrenous necrosis4. Caseous necrosis5. Fat necrosis6. Fibrinois necrosis

Causes of cell injury

1. Hypoxia


2. Physical agents


3. Chemical agents & drugs


4. Infectious agents


5. Immunological reactions


6. Genetic abnormalities


7. Nutritional Imbalances

Morphological change in apoptosis

- Cell shrinkage


- Chromtin condensation


- Formation of cytoplasmic blebs and apoptotic bodies


- Phagocytosis of apoptotic cells or cell bodies, usually by macrophages

Types of BCL

1. Anti-apoptotic


(BH1-4)


- BCL2, BCL-XL, MCL1



2. Pro-apoptotic


(BH1-3)


- BAX, BAK



3. Regulated apoptosis initiators


(BH3 only)


- BAD, BIM, BID, Puma, Nox