Cell Cycle

Front 1

3 Checkpoint locatins

Back 1

1. G1-S(start)
2. G2-M
3. Trigger anaphase

Front 2

G1/S-cyclin class

Back 2

Starts in the late G1, triggers the start and falls off in S

Front 3

S-cyclin class

Back 3

Occurs after start and works on duplucation and falls of in M

Front 4

M-cyclin

Back 4

Occurs in G2 and enters into anaphase and falls off mid-M

Front 5

Wee1 kinase

Back 5

Occurs during inhibitory phosphorylation of cdks when an additional phosphate is added. Typical for M-cdk

Front 6

cdk inhibitor proteins(CKI)

Back 6

These proteins bind to the complex to disrupt the active site.

Front 7

CAK(cdk-activating kinases)

Back 7

Increase the complex's activity

Front 8

What decreases a checkpoints control mechanism?

Back 8

Additional phosphates(Wee1) and cdk inhibitory proteins(CKIs)

Front 9

Proteolysis

Back 9

Digestion of proteins that have been marked with ubiquitin by proteases. Used as a way to regulate control mechanisms in the cell cycle

Front 10

2 ways to regulate regulators

Back 10

1. Proteolysis
2. Synthesis