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29 Cards in this Set
- Front
- Back
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Characterization of Cartilage
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1. ECM rich in GAG's and proteoglyns
2. form large marcomolecules that interact with collegen and elastic fibers 3. Resist compression, bear machanical forces without permanent distorsion. |
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Function of Cartilage
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1. Absorp shock
2. provide smooth surface for articular sufaces 3. support surrounding tissues for growth and development of long bones |
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Chondrocytes
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1.make components of ECM, collegen fibers and constituents of ground substance
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Where do chondrocytes sit?
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Lacunae
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Extracellular Matrix of Cartilage is composed of What?
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1. Fibers (collegen type I, II, and lesser extent 9,10,11..elastic fibers)
2. Glycosaminoglycans (GAGs) |
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What is Perichondrium?
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1. Dense irregular CT
2. Surrounds many types of cartilage 3. Outter fibrous layer 4. Inner cellular layer (source of cells that can divide and differeciate into chondrocytes) |
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Hyaline
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Characteristics: Type II
Perichondrium: present in most, except articular cartilages and epiphyses Location: articular ends of long bones, nose, larynx, trachea, bronchi, ventral ends of ribs MOST ABUNDANT TYPE |
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Elastic
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Characteristic: Type II and elastic
Perichondrium: Present Location: Pinna of ear, auditory canal, auditory tube, epiglottis, |
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Fibrocartilage
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Characteristics: Type I, Always associated with dense regular CT
Perichondrium: absent Location: menisci, IV discs, articular discs, pubic symphysis, ligaments and tendons |
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What is an aggrecans?
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Macromolcule that holds lots of water, hoold to chondrocyte, HA and proteoglycans
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What can you find in Hyaline cartilage Matrix?
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1) Type II collagen
2) aggrecans |
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why is chondroitin sulfate important in hyaline cartilage?
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It is a side chain of proteoglycans and it can bind to the collagen fibrils, forming a cross-linked matrix.
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Name 3 cartilage cells?
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1) chondrogenic cells
2) chondroblasts 3) chondrocytes |
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When a cartilage cell is completely surrounded by ECM, it is called?
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a chondrocyte
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Interterritorial matrix
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1)has fewer GAG's in ECM
2)a lot of collagen fibrils 3)between the cartilage cells, |
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Territorial matrix
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1) has an increased concentration of GAG's
2) arrounds peripheral of chondrocyte |
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What cartilage cells are located in the perichondrium?
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chondrogenic cells
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name the 2 types of growth of hyaline cartilage?
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1) interstitial
2) appositional |
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How do Tissues without perichondrium grow?
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interstitial growth
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Interstitial growth
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Growth from within cartilage
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appositional growth
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Growth comes from addition of chondrocytes from adding to the outside
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What type of cartilge looks like "bacon and eggs"
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fibrocartilage
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What are the two types of joints we are talking about in regards to cartilage?
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Synarthroses and diarthroses
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What are three characteristics dealing with diarthroses?
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1)articular cartilage
2) Joint capsule 3) synovial membrane |
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Diarthroses-articular cartilage
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Type II collegen
lots of GAG's |
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Diarthroses-Joint capsule
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Dense irregular CT
Type I collagen (orriented in all directions) inner layer-synovial membrane |
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Diarthroses-synovial membrane
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1)Good at regenerating
2)fibrous 3)CT membrane, no Basal membrane 4) no adhering junctions 5) Take plasma from capillaries |
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Function of synovial fluid
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fluid nutrition and o2 for articular cartilage that has no perichondrium
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Gothic arch pattern
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Collagen fibers are arranged perpendicular to surface deep and when closer to surface are parallel. Helps distribute load over greater area. In articular surfaces of diarthroses joints
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