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65 Cards in this Set

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  • Back
What is the target of the nuclear localization signal?
Nucleus
What is the consenses sequence of the nuclear localization signal?
String of Primary Basic Amino Acids Toward Middle
What is the location of the nuclear localization signal?
Internal
What is the cleavability of the nuclear localization signal?
Noncleavable
What is the target of the N-Terminal Cleavable Signal Sequence
Lumen of ER
What is the consensus sequence of the N-Terminal Cleavable Signal Sequence?
20 Amino Acids, start with Arganine followed by stretch of hydrophobic residues
What is the location of the N-Terminal Cleavable Signal Sequence?
N-terminus
What is the cleavability of the N-Terminal Cleavable Signal Sequence?
Cleavable
What is the target of the STOP Transfer Sequence?
ER Membrane
What is the consensus sequences of the STOP Transfer Sequence?
20-25 Amino Acids that forms an Alpha Helix, primary
What is the location of the STOP Transfer Sequence?
Internal
What is the cleavability of the STOP Transfer Sequence?
Noncleavable
What is the target of the Internal Non-Cleavable Signal Sequence?
ER Membrane
What is the consensus sequences of the Internal Non-Cleavable Signal Sequence?
20-25 Amino Acids that forms an Alpha Helix or multiple with Stop Transfer
What is the location of the Internal Non-Cleavable Signal Sequence?
Internal
What is the cleavability of the Internal Non-Cleavable Signal Sequence?
Noncleavable
What is the target of the Retention Retrieved Signal?
From ER to Golgi Apparatus
What is the consensus sequence of the Retention Retrieved Signal?
KDEL (Lysine, Aspartic Acid, Glutamic Acid, Lucine) , KKXX (Lysine, Lysine, X, X)
What is the location of the Retention Retrieved Signal?
C-Terminal
What is the cleavability of the Retention Retrieved Signal?
Noncleavable
What is target of the Signal Patch?
Lysosome
What is the consensus sequence of the Signal Patch?
3D Location on a protein, not primary
What is the location of the Signal Patch?
3D
What is the cleavability of the Signal Patch?
Noncleavable
What is the target of the Nuclear Export Signal?
Outside of Nucleus
What is the consensus sequence of the Nuclear Export Signal?
Specific Amino Acid Sequence
What is the location of the Nuclear Export Signal?
Internal
What is the target of the Presequence?
Matrix of Mitochondria
What is the consensus sequence of the Presequence?
15-35 N-terminal, Positively changed Amino Acids, folds into amphipathic Alpha Helix
What is the location of the Presequence?
N-terminus
What is the cleavability of the Presequence?
Cleavable
What is the target of the N-Myristolation?
Inner Face of Plasma Membrane
What is the consensus sequence of the N-Myristolation?
Mystric acid attaches to N-Terminus glycine residues after methionine is removed
What is the location of the N-Myristolation?
N-terminus
What is the target of Prenylation?
Inner Face of Plasma Membrane
What is the consensus sequence of Prenylation?
Prenyl groups; attach to sulfur atoms of cysteine residue at C-Terminus
What is the location of Prenylation?
C-Terminal
What is the location of Palmitaglation?
Inner Face of Plasma membrane
What is the consensus sequence of Palmitaglation?
Palmitic Acid attaches to sulfur atoms of internal cysteine residue
What is the location of Palmitaglation?
Internal
What is the target of GPI Anchors?
External Face of Plasma Membrane
What is the consensus sequence of GPI Anchors?
Lipids add to C-Terminus end of proteins through oligosaccharide
What is the location of GPI Anchors?
C-Terminal
What is the cleavability of GPI Anchors?
Cleavable
What is the target of Transit Peptide?
Stroma of Chloroplast
What is the consensus of Transit Peptide?
30-100 amino acids
What is the location of the Transit Peptide?
N-Terminus
What is the cleavability of the Transit Peptide?
Cleavable
What is the target of the Hydrophobic Signal Sequence?
Thylakoid Lumen of Chloroplast
What is the consensus sequence of the Hydrophobic Signal Sequence?
Hydrophobic Amino Acids
What is the location of the Hydrophobic Signal Sequence?
N-Terminus
What is the cleavability of the Hydrophobic Signal Sequence?
Cleavable
What is the target of the Peroxisome Targeting Signal I (PTS-I)?
Perioxisome
What is the consensus sequence of the Peroxisome Targeting Signal I (PTS-I)?
SKL (Serine, Lysine, Lucine)
What is the location of the Peroxisome Targeting Signal I (PTS-I)?
C-Terminal
What is the cleavability of the Peroxisome Targeting Signal I (PTS-I)?
Noncleavable
What is the target of the Peroxisome Targeting Signal II (PTS-II)?
Perioxisome
What is the consensus sequence of the Peroxisome Targeting Signal II (PTS-II)?
9 Specific Amino Acids
What is the location of the Peroxisome Targeting Signal II (PTS-II)?
N-Terminus
What is the cleavability of the Peroxisome Targeting Signal II (PTS-II)?
Noncleavable
What is the target of the Manose-6-Phosphate on an N-linked Carbon?
Lysosome
What is the consensus sequence of the Manose-6-Phosphate on an N-linked Carbon
Nonprotein
What is the target of the Glycolipids?
External face of the Plasma Membrane
What is the consensus sequenc of the Glycolipids?
Added to C-Terminus Carboxyl groups of some proteins
What is the location of the Glycolipids?
C-Terminal