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65 Cards in this Set
- Front
- Back
What is the target of the nuclear localization signal?
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Nucleus
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What is the consenses sequence of the nuclear localization signal?
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String of Primary Basic Amino Acids Toward Middle
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What is the location of the nuclear localization signal?
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Internal
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What is the cleavability of the nuclear localization signal?
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Noncleavable
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What is the target of the N-Terminal Cleavable Signal Sequence
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Lumen of ER
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What is the consensus sequence of the N-Terminal Cleavable Signal Sequence?
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20 Amino Acids, start with Arganine followed by stretch of hydrophobic residues
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What is the location of the N-Terminal Cleavable Signal Sequence?
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N-terminus
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What is the cleavability of the N-Terminal Cleavable Signal Sequence?
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Cleavable
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What is the target of the STOP Transfer Sequence?
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ER Membrane
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What is the consensus sequences of the STOP Transfer Sequence?
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20-25 Amino Acids that forms an Alpha Helix, primary
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What is the location of the STOP Transfer Sequence?
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Internal
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What is the cleavability of the STOP Transfer Sequence?
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Noncleavable
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What is the target of the Internal Non-Cleavable Signal Sequence?
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ER Membrane
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What is the consensus sequences of the Internal Non-Cleavable Signal Sequence?
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20-25 Amino Acids that forms an Alpha Helix or multiple with Stop Transfer
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What is the location of the Internal Non-Cleavable Signal Sequence?
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Internal
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What is the cleavability of the Internal Non-Cleavable Signal Sequence?
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Noncleavable
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What is the target of the Retention Retrieved Signal?
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From ER to Golgi Apparatus
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What is the consensus sequence of the Retention Retrieved Signal?
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KDEL (Lysine, Aspartic Acid, Glutamic Acid, Lucine) , KKXX (Lysine, Lysine, X, X)
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What is the location of the Retention Retrieved Signal?
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C-Terminal
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What is the cleavability of the Retention Retrieved Signal?
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Noncleavable
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What is target of the Signal Patch?
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Lysosome
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What is the consensus sequence of the Signal Patch?
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3D Location on a protein, not primary
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What is the location of the Signal Patch?
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3D
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What is the cleavability of the Signal Patch?
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Noncleavable
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What is the target of the Nuclear Export Signal?
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Outside of Nucleus
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What is the consensus sequence of the Nuclear Export Signal?
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Specific Amino Acid Sequence
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What is the location of the Nuclear Export Signal?
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Internal
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What is the target of the Presequence?
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Matrix of Mitochondria
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What is the consensus sequence of the Presequence?
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15-35 N-terminal, Positively changed Amino Acids, folds into amphipathic Alpha Helix
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What is the location of the Presequence?
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N-terminus
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What is the cleavability of the Presequence?
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Cleavable
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What is the target of the N-Myristolation?
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Inner Face of Plasma Membrane
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What is the consensus sequence of the N-Myristolation?
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Mystric acid attaches to N-Terminus glycine residues after methionine is removed
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What is the location of the N-Myristolation?
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N-terminus
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What is the target of Prenylation?
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Inner Face of Plasma Membrane
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What is the consensus sequence of Prenylation?
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Prenyl groups; attach to sulfur atoms of cysteine residue at C-Terminus
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What is the location of Prenylation?
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C-Terminal
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What is the location of Palmitaglation?
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Inner Face of Plasma membrane
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What is the consensus sequence of Palmitaglation?
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Palmitic Acid attaches to sulfur atoms of internal cysteine residue
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What is the location of Palmitaglation?
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Internal
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What is the target of GPI Anchors?
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External Face of Plasma Membrane
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What is the consensus sequence of GPI Anchors?
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Lipids add to C-Terminus end of proteins through oligosaccharide
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What is the location of GPI Anchors?
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C-Terminal
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What is the cleavability of GPI Anchors?
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Cleavable
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What is the target of Transit Peptide?
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Stroma of Chloroplast
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What is the consensus of Transit Peptide?
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30-100 amino acids
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What is the location of the Transit Peptide?
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N-Terminus
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What is the cleavability of the Transit Peptide?
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Cleavable
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What is the target of the Hydrophobic Signal Sequence?
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Thylakoid Lumen of Chloroplast
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What is the consensus sequence of the Hydrophobic Signal Sequence?
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Hydrophobic Amino Acids
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What is the location of the Hydrophobic Signal Sequence?
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N-Terminus
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What is the cleavability of the Hydrophobic Signal Sequence?
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Cleavable
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What is the target of the Peroxisome Targeting Signal I (PTS-I)?
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Perioxisome
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What is the consensus sequence of the Peroxisome Targeting Signal I (PTS-I)?
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SKL (Serine, Lysine, Lucine)
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What is the location of the Peroxisome Targeting Signal I (PTS-I)?
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C-Terminal
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What is the cleavability of the Peroxisome Targeting Signal I (PTS-I)?
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Noncleavable
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What is the target of the Peroxisome Targeting Signal II (PTS-II)?
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Perioxisome
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What is the consensus sequence of the Peroxisome Targeting Signal II (PTS-II)?
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9 Specific Amino Acids
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What is the location of the Peroxisome Targeting Signal II (PTS-II)?
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N-Terminus
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What is the cleavability of the Peroxisome Targeting Signal II (PTS-II)?
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Noncleavable
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What is the target of the Manose-6-Phosphate on an N-linked Carbon?
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Lysosome
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What is the consensus sequence of the Manose-6-Phosphate on an N-linked Carbon
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Nonprotein
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What is the target of the Glycolipids?
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External face of the Plasma Membrane
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What is the consensus sequenc of the Glycolipids?
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Added to C-Terminus Carboxyl groups of some proteins
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What is the location of the Glycolipids?
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C-Terminal
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