Cell Bio Final

Front 1

Some pharmaceutical companies are trying frantically to find inhibitors of telomerase. Such a drug could, in theory, be used to

Back 1

cure cancer

Front 2

The human female has 23 DIFFERENT chromosomes, whereas the human male has 24 DIFFERENT ones.

Back 2

20%

Front 3

Human DNA contains 20% C on a molar basis. The percentage of G on a molar basis would be

Back 3

a. true

Front 4

Which of the following is an essential element of plasmids used as cloning vectors

Back 4

an origin of replication

Front 5

. If a cellular homogenate was subjected to differential centrifugation, which of the following would be expected to pellet first?

Back 5

nuclei

Front 6

The EXACT site of ribosomal RNA synthesis is

Back 6

nucleolus

Front 7

DNA is condensed as chromosomes for a very short time during interphase.

Back 7

FALSE

Front 8

The human genome is comprised of 23 pairs of chromosomes found in nearly every cell in the body. Each cell would have how many replication origins?

Back 8

>200

Front 9

When conducting research to determine which viral macromolecule actually entered an infected cell, 32P and 35S isotopes were used to grow the virus particles. The 35S would label

Back 9

protein

Front 10

Heterochromatin is

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transcriptionally inactive

Front 11

Tertiary structure of a protein. The interior has amino acids.

Back 11

hydrophobic

Front 12

The type of chromatography which could be usedto separate protein A (MW 36,000 daltons, pI 7.3) from protein B (MW 937,000 daltons, pI 7.3) upon this given data is

Back 12

molecular sieve

Front 13

Protein A and B were analyzed by 2D gel electrophoresis.The diagram on the right is the result. We can conclude that

Back 13

protein A is larger than B

Front 14

Regulation of protein activity by phosphorylation and dephosphorylation requires

Back 14

kinase

Front 15

Which level of protein structure is held together by hydrophobic interactions between non-polar side chains and hydrogen bonds between polar side chains?

Back 15

tertiary

Front 16

A compact and stable folded region of polypeptide usually related to a specific function is called a

Back 16

domain

Front 17

. A single protein may have both alpha helical and beta pleated sheet secondary structures

Back 17

TRUE

Front 18

Cys may play a role in

Back 18

a. primary structure b. secondary structure c. tertiary structure d. quarternary structure e. a, c and d

Front 19

The isomeric form of amino acids that living organisms are able to utilize is

Back 19

L

Front 20

The 6 common atoms in living systems: H, C, N, P, O and S each form a characteristic number of covalent bonds. For C, this number is

Back 20

4

Front 21

. The synthesis of macromolecules by polymerization of monomeric subunits typically proceeds by

Back 21

dehyration

Front 22

The member of the pair at the right that H2C=CH2 H3C-CH3 is most reduced is

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B

Front 24

Which of the following reactions are energetically favorable

Back 24

sucrose--CO2+H2O

Front 25

Energetically favorable reactions are those that

Back 25

decrease the free energy of a system

Front 26

Which of the following features generally tend to increase the number of catalytic events an enzyme accomplishes per second?

Back 26

increased substrate concentration

Front 27

Competitive inhibitors

Back 27

don’t change the Vmax of a rxn

Front 28

The larger the binding energy between E and S, the larger the KM and the more likely they will be paired.

Back 28

FALSE

Front 29

. Activated carriers, such as ATP, acetyl-CoA, transfer chemical groups.

Back 29

TRUE

Front 30

. Fatty acids are

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amphipathic

Front 31

. Over the course of a day, in a normal individual the circulating levels of glucose vary around a mean of 90 mg/dL. What would this value be expressed as a molar concentration of glucose in blood, which is the way it is typically reported in the rest of the world? The MW of glucose is 180.

Back 31

5x10 -3

Front 32

Radioisotopes differ from the normal, nonradioactive form of their elements by

Back 32

# neutrons

Front 33

Avagadro’s number 6.023 x 1023 indicates

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#molec in 1 mole of given sub

Front 34

All catabolic reactions involving macromolecules require input of

Back 34

water

Front 35

DNA is negatively charged at physiological pH. A protein Z binds to DNA through noncovalent ionic interactions involving lysines. What will be the effect of acetylation of the lysine side chains (see figure) in protein Z on the strength of this binding?

Back 35

) It should decrease because the acetylated lysine no longer has a positive charge.

Front 36

Covalent bonds could be used in place of noncovalent bonds to mediate most of the biochemical reactions of macromolecules.

Back 36

F

Front 37

If oxidation occurs in a biochemical reaction, it is always accompanied by a reduction reaction.

Back 37

TRUE

Front 38

We humans use oxidation reactions to extract energy from food molecules.

Back 38

TR

Front 39

All of the following contain double membranes EXCEPT

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liposomes, cells, lysosomes

Front 40

Given what you know about the differences between procaryotic cells and eucaryotic cells, which of the following processes would not be to study in the model organism, E. coli.

Back 40

how mitochondria get distributed to cells during cell division

Front 41

Which of the following is not a characteristic or distinction of living organisms?

Back 41

high organ. Cmpd to non living

Front 42

Of the following items, the smallest is

Back 42

ribosome

Front 43

The specialized cell types in the body of a multicellular organism are different from each other chiefly because

Back 43

diff genes are switched on in diff cell types

Front 44

Which of the following cellular structures or compartments is found in both eukaryotes and prokaryotes.

Back 44

ribosome

Front 45

Which of the following statements about the basic chemistry of cells is TRUE?

Back 45

The genetic instructions in all cells are stored in DNA

Front 46

Mitochondria take in carbon dioxide and release oxygen

Back 46

FALSE

Front 47

Yeasts are

Back 47

eucaryotes

Front 48

Which membrane of mitochondria was derived from the cell membrane of the ancestral eucaryotic cell ?

Back 48

outer