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23 Cards in this Set
- Front
- Back
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where would you get histones from |
calf thymus |
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where would you get actin from
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rabbit muscle
rAbbit |
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where would you get tubulin from |
cow brain caTTle |
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Formin |
nucleates assembly and remains associated with the growing plus end of actin |
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arp 2/3 complex |
nucleates assemble and remains attached at the minus end, forms a web of actin |
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profilin |
binds subunits and speeds elongation of actin |
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thymosin |
binds subunits and slows elongation of actin |
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tropomyosin |
stabilizes actin filaments |
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gelsolin |
severs filaments and binds to plus end of actin |
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cofilin |
binds adp-actin and accelerates dissassembly of actin |
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tropomodulin |
capping protein at minus end of actin
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filamin |
gel formation by clamping 2 actin filaments at approx. 90 degree angles, important for lamellipodia |
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gamma turc |
nucleates assembly and remains associated with the minus end |
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centrosome |
recruits the gamma turcs |
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+TIPS |
remain associated with growing plus ends and can link them to other structures such as membranes |
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XMAP215 |
stabilizes plus ends and accelerates assembly |
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MAPS |
stabilizes microtubules by binding along sides |
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katanin |
severs microtubules |
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kinesin |
introduces catastrophe |
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stathmin |
binds subunits and prevents assembly |
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tau and map2 |
bundle and cross link filaments |
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plectin |
links microtubules to intermediate filaments |
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what regulates formin? |
Rho GTP-ases |
