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34 Cards in this Set
- Front
- Back
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Metformin's Brand?
Brands for Thiazolidines? Brands for SU? Non-SU sec? Brands? brands for alpha glucose? Amylin ant? Intecretin Memetics DPPIV Inbib |
*Glucophage
*Pio- ACTOS Rosi-AVANDIA *glyburide-GLYNASE, Diabeta, Micronase, gllipizide: glucatrol *Repaglinde-AMARYL nateglinde STARLIX *SYMLIn, pramlintide *exenatide BYETTA *stitaglyptin JANUVIA |
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MOA alpha glucosidase inhib?
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delays CHO abs/breakdown
-acarbos-PRECOSE, miglitol- Glyset |
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Which drugs effect PPG
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Non SU
Amylin agonist intecrine memetics Dpp4 inhin |
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MOA of DPP4
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inhib breakdown of intecrine hormones
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Dosing Glyburide: start Max
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2.5 20 max divide >10
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Dosing NON SU
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nategline (starlix) 60 mg g 30 min before each meal
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Dosing metformin
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500 qd/BID with largest Meal
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Dosing ACTOS
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pioglit 15 mg qd, max 45
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Dosing acarbos
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25 mg qd-TID max 100TID
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Dosing intecrine
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Byetta 5 mcq SQ BID
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dosing DP4
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Sitagliptin 100 mg
50 or 25 if RF or 3a4 inhibitor |
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SE metformin
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GI
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SE TZD
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Weight Gain, Fluid Retent, HF, Fractures Hepatox, Lipids
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SE alpha Glucosidase
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Flatulence GI pain Hepatox
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SE intecrine
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hypoG(with SU) Gi Pancreatitis TUMOR RF
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CI RF
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Metformin SU BYETTA
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CI LF
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SU TZD A GLUCOSE
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CI HF
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Metformin TZD
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CI FATTIES
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TZD SU NoN SU
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CI hyperglycemia
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Amylin intecrine SU NON SU
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WHAT SHOULD FATTIEES USE?
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MEtformin DP3 integrine amylin alpha gkucoseagase
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most effective DM TX
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Basil insulin
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LEast Expensive DMTX
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SU
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Least Hypoglycemia DM TX
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Glitazone
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MOST INtensive Insulin Regimine
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Intensive insulin + Metformin + Glitazone
NO SU |
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VTE Px Strategy LOW
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Ambulation
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VTE Px Strategy Mod/High
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UFH 5000
IPC Dalteparin 5k u sq qd Lovenox 40 mg sq qd |
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VTE Px Strategy Highest
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UFH 5000 sq Q 8 hrs +IPC
Lovenox 30 mg sq q12 |
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Tx of VTE
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Heparin 80 u/kg BOLUS
With 18 U/kg/hr Check apTT in 6hrs Lovenoc 1mg/kg q 12 monitor platelets Give Warfarin and remove HEP after 4 days |
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How to adjust Hep
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look at Appt
if 45-70 no Change if 70-90 Dec by 2 u/kg if >90 HOLD 1 HR & dec By 3 ukg if 35 to 45 40 u/kg bolus inc 2 <35 90 ukg bolus inc 4 |
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How long for warfarin tx
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2nd offence- Indefinate
Idopathic of hypercoad 6-12 Transient 3 months Malig LMWH 3-6 m then indef WARF |
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Tx of VTE if HIT
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Consider FAILURESE
if Liver Give Lepirudin If Renal give agatroban |
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Pathophys of MS
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Risk Factors influence CV disease.
Ondominal adiposity influences insulin resistance ; tissues do not respond no hepatic glucose inhibition, no supression of lypolyiss, Free fatty acids will further exacerbate resistance and become more intraabdominal fat. Also precipitates dislipidemia, and htn |
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How long each insulin Works
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rapid 4
short 6 NPH 12 |
