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28 Cards in this Set
- Front
- Back
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CD21
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B Cell marker
EBV receptor also CR2 of the complement path |
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CD40
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on B cells to bind with CD40L on T Cells
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CD2
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sheep red blood cell receptor on all T cells
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CD3
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signal transduction marker on all T cells
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CD28
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on T cells for T cell activation; binds to B7s on activated B cells
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Secreted by TH1
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IL-2 and IFN-gamma
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secreted by Th2
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IL 4,5,6,10
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B Cell markers?
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CD 19, 20, 21, 40
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INF gamma
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activates macrophages to secrete its cutokines
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CD 16
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NK cells
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NK Cell cd antigens
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CD 16, CD 57, CD 56
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Monocyte CD antigens
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CD 14, CD 16
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Ligand for FcgammaIII receptor
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CD16
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Cells with CD 2
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T cells, NK cells
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IL-2
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stimulates proliferation of T cell
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Cd28-B7 binding
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stimulates IL-2 secretion
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CD3 induces what?
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CD40 ligand and IL-2 R expression on T cell
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CD40-CD40L binding causes what?
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B7 expression by B cells
required for class switching |
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Cytokines secreted by activated THo cell?
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IL-2, IL-4 , IFN gamma to induce macrophage
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neutrophil chemotaxis cytokine
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IL-8
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cytokine that inhibits cellular immunity
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IL-10
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secreted by TH2
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IL4,5,6 to cause b cell differentiation
and IL-10 to inhibit cellular immunity. |
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IFN gamma (two roles)
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stimulate macrophage and inhibit TH2 proliferation
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IL-4 (two roles)
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inhibits macrophage activation and B cell diffentiation
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IL-12
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NK cell activation in inflammation
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IL-13
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IgE synthesis
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IL-6
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secreted by TH2 cells
stimulates synthesis of acute phase proteins in inflammation |
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CD 80 and CD 86
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same thing as B7 molecules expressed after CD40-CD40 binding
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